{"title":"Home page","description":null,"products":[{"product_id":"kmc-nrg-gel-energy-gel-refill-pouch-mint-caffeine-10-x-70g-serves","title":"KMC NRG GEL+ Energy Gel Refill Pouch Mint Caffeine (10 x 70g Serves)","description":"\u003cp\u003e\u003cspan\u003eThe new refillable KMC NRG GEL removes the need for single-use plastic gel sachets, reduces packaging waste by over 60%. Combine your refill pouch with our ultra-durable, pocket-sized, refillable KMC X Hydrapak 150ml Gel Soft Flask.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eOur intelligent Dual Charge Formula™ - A dual-carbohydrate, electrolyte and B vitamin Isotonic formula which provides fast, tasty energy without upsetting your stomach by using Natural Peppermint as an anti-inflammatory. Plus, it's vegan \u0026amp; gluten free.\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cmeta charset=\"utf-8\"\u003ePlease note: KMC Refill gels are \u003cspan style=\"text-decoration: underline;\"\u003eNOT\u003c\/span\u003e tested by Informed Sport.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eRecharge your Fueling strategy today and choose Nutrition Crafted for Champions. Everest-Tested, Athlete-Approved, built to Conquer Any Challenge, Any Everest.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"banner__heading inline-richtext h2\"\u003eCONQUER YOUR EVEREST.\u003c\/p\u003e","brand":"Kendal Mint Co®","offers":[{"title":"Gel Refill Pouch Only","offer_id":53230497038664,"sku":"GEL132","price":15.93,"currency_code":"GBP","in_stock":true},{"title":"Bundle: Gel Refill Pouch \u0026 Flask","offer_id":53230497071432,"sku":"GEL132+BOT801","price":31.85,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0968\/7603\/6424\/files\/refillable-reusable-energy-gel-soft-flask-150ml-upgraded-bite-valve-for-kmc-nrg-gel-kendal-mint-co-flask-854813.jpg?v=1780565332"},{"product_id":"raw-chocolate-signature-dark","title":"Raw Chocolate Signature Dark","description":"\u003cp\u003e\u003cspan\u003eSignature Dark is bold and smooth, with rich cocoa notes that melt in your mouth.\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cspan\u003eCompletely vegan and made in the UK with simple and recognisable ingredients, Snacksy Raw Bars are proudly gluten and dairy free. Snacksy Signature Dark 61% is a crowd favourite, known for it’s pure cocoa flavour. Our Signature bar is an ideal snack for chocolate lovers searching for a healthier alternatives or bakers looking for a smooth chocolatey taste.\u003c\/span\u003e\u003c\/p\u003e","brand":"Snacksy","offers":[{"title":"4","offer_id":53230496940360,"sku":"50888396013898","price":9.99,"currency_code":"GBP","in_stock":true},{"title":"6","offer_id":53230496973128,"sku":"50888396046666","price":13.49,"currency_code":"GBP","in_stock":true},{"title":"12","offer_id":53230497005896,"sku":"50888396079434","price":24.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0968\/7603\/6424\/files\/CopyofSignatureDark_Whitebackground_Back.jpg?v=1780565334"},{"product_id":"kmc-nrg-gel-citrus-mint-flavour-bundle-l-48x70g-gels","title":"KMC NRG GEL Citrus \u0026 Mint Flavour Bundle L (48x70g Gels)","description":"\u003cp\u003e\u003cspan\u003eFuel up quickly and effectively with KMC NRG GEL. Our intelligent Dual Charge Formula™ - A dual-carbohydrate, electrolyte and B vitamin Isotonic formula which provides fast, tasty energy without upsetting your stomach by using Natural Peppermint as an anti-inflammatory. Plus, it's vegan, gluten free, and tested by Informed Sport for athletes' peace of mind. \u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eRecharge your Fueling strategy today and choose Nutrition Crafted for Champions. Everest-Tested, Athlete-Approved, built to Conquer Any Challenge, Any Everest.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"banner__heading inline-richtext h2\"\u003eCONQUER YOUR EVEREST.\u003c\/p\u003e","brand":"Kendal Mint Co®","offers":[{"title":"Default Title","offer_id":53230497628488,"sku":"BUN102","price":79.68,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0968\/7603\/6424\/files\/kmc-nrg-gel-citrus-mint-flavour-bundle-l-48x70g-gels-kendal-mint-co-bundle-947002.jpg?v=1780565331"},{"product_id":"nomu-mm-all-purpose-batter","title":"NOMU MM All Purpose Batter","description":"\u003cp\u003eThe magic of MiniMakes lies in the versatility of the mixes! The perfect way to bake to save time and ingredients and to reduce waste. Enough for 4 to 6 or simply double up your mix!\u003cbr\u003e\u003c\/p\u003e\n\u003cp data-start=\"633\" data-end=\"742\"\u003eOne mix, endless possibilities. From cupcakes to pancakes, this versatile batter is your baking blank canvas.\u003c\/p\u003e\n\u003cp\u003e\u003cspan data-contrast=\"auto\" lang=\"EN-ZA\" class=\"TextRun SCXW63229900 BCX9\"\u003e\u003cstrong\u003e\u003cspan class=\"NormalTextRun SCXW63229900 BCX9\"\u003eContains\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"NormalTextRun SCXW63229900 BCX9\"\u003e\u003cstrong\u003e:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"NormalTextRun SCXW63229900 BCX9\"\u003eWheat and Gluten\u003c\/span\u003e\u003c\/span\u003e\u003cspan data-ccp-props='{\"201341983\":0,\"335551550\":2,\"335551620\":2,\"335559739\":200,\"335559740\":276}' class=\"EOP SCXW63229900 BCX9\"\u003e \u003c\/span\u003e\u003cbr\u003e\u003cstrong\u003eShelf life:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e18 months\u003cbr\u003e\u003cstrong\u003eStorage instructions:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003ePlease store in a cool, dry place.\u003c\/p\u003e\n\u003cp\u003e\u003cimg sizes=\"(max-width: 203px) 100vw, 203px\" srcset=\"https:\/\/nomu.co.za\/wp-content\/uploads\/2023\/06\/Certifications-300x89.png 300w, https:\/\/nomu.co.za\/wp-content\/uploads\/2023\/06\/Certifications.png 579w\" height=\"60\" width=\"203\" alt=\"\" src=\"https:\/\/nomu.co.za\/wp-content\/uploads\/2023\/06\/Certifications-300x89.png\" class=\"alignnone wp-image-23161\" decoding=\"async\"\u003e\u003c\/p\u003e","brand":"Mahdina","offers":[{"title":"1 Unit","offer_id":53230497104200,"sku":"BAK0034","price":3.97,"currency_code":"GBP","in_stock":true},{"title":"2 Units","offer_id":53230497136968,"sku":"BAK0034","price":7.49,"currency_code":"GBP","in_stock":true},{"title":"4 Units","offer_id":53230497169736,"sku":"BAK0034","price":13.49,"currency_code":"GBP","in_stock":true},{"title":"8 Units","offer_id":53230497202504,"sku":"BAK0034","price":23.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0968\/7603\/6424\/files\/IMG_0028_8bb301c6-2a26-4499-9b61-bf728cb71aed.png?v=1780565333"},{"product_id":"kmc-nrg-gel-citrus-mint-energy-gel-70g","title":"KMC NRG GEL Citrus \u0026 Mint Energy Gel 70g","description":"\u003cp\u003e\u003cspan\u003eFuel up quickly and effectively with KMC NRG GEL. Our intelligent Dual Charge Formula™ - A dual-carbohydrate, electrolyte and B vitamin Isotonic formula which provides fast, tasty energy without upsetting your stomach by using Natural Peppermint as an anti-inflammatory. Plus, it's vegan, gluten free, and tested by Informed Sport for athletes' peace of mind. \u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eRecharge your Fueling strategy today and choose Nutrition Crafted for Champions. Everest-Tested, Athlete-Approved, built to Conquer Any Challenge, Any Everest.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"banner__heading inline-richtext h2\"\u003eCONQUER YOUR EVEREST.\u003c\/p\u003e","brand":"Kendal Mint Co®","offers":[{"title":"12 x 70g","offer_id":53230497759560,"sku":"GEL211","price":21.24,"currency_code":"GBP","in_stock":true},{"title":"6 x 70g","offer_id":53230497792328,"sku":"GEL201(6)","price":11.68,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0968\/7603\/6424\/files\/GEL211productfrontimage_boxSQ.png?v=1780565332"},{"product_id":"kmc-pro-mix-whey-protein-recovery-powder-super-bundle-90-x-40g","title":"KMC PRO MIX Whey Protein Recovery Powder Super Bundle (90 x 40g)","description":"\u003cp\u003e\u003cspan data-mce-fragment=\"1\"\u003eExperience accelerated recovery when you add KMC PRO MIX Whey Protein Recovery Powder to your routine! This delicious Chocolate Mint flavoured powder is easy on the stomach and packed with premium whey protein for fast and effective results. Tested safe for athletes, it's also Vegetarian and Gluten-Free.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan data-mce-fragment=\"1\"\u003eTrain hard, recover faster with KMC PRO MIX!\u003c\/span\u003e\u003c\/p\u003e","brand":"Kendal Mint Co®","offers":[{"title":"Default Title","offer_id":53230497923400,"sku":"POW201(90)","price":159.36,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0968\/7603\/6424\/files\/POW201KMCPROMIXChocolateMintProteinRecoveryPowderbyKendalMintCo90x40gfrontShadowSQ.jpg?v=1780565331"},{"product_id":"cycle-performance-nutrition-pack","title":"Cycle Performance Nutrition Pack","description":"\u003cdiv class=\"\"\u003e\u003cspan class=\"j2store-product-content-field j2store-product-content-field-1\"\u003eThe KMC Cycle Nutrition Pack contains a combination of our most popular Energy Bars, Energy Gels, Hydration and Recovery products for your next cycling training session or event. Plus a 100% Biodegradable \u0026amp; Customisable 500ml or 750ml Bottle\/ Bidon.\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv class=\"\"\u003e\n\u003cdiv class=\"\"\u003e\n\u003cp style=\"background-color: #f8f9fa; padding: 15px; border-left: 4px solid #28a745; margin: 20px 0; display: flex; gap: 15px; align-items: flex-start;\"\u003e\u003cspan style=\"flex: 1;\"\u003e\u003cb\u003eUpgrade to 17 Products — for only +£4.99\u003c\/b\u003e\u003cbr\u003eAdd 4 extra bestsellers for just\u003cstrong\u003e +£4.99\u003c\/strong\u003e (RRP \u003cb\u003e£6.98\u003c\/b\u003e - \u003cstrong\u003esave\u003c\/strong\u003e \u003cb\u003e29%\u003c\/b\u003e)\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eExtras Included:\u003c\/strong\u003e 3 bars + 1 ISO MIX serving (Raspberry \u0026amp; Mint).\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eChoose your upgrade:\u003c\/strong\u003e\u003cbr\u003e\u003ca href=\"https:\/\/www.kendalmint.co.uk\/cart\/54853515772286:1,56829326164350:1\" title=\"Add Cycle Pack + Upgrade\"\u003e\u003cstrong\u003eAdd Green Bottle + Upgrade to Cart\u003c\/strong\u003e\u003c\/a\u003e\u003cbr\u003e\u003ca href=\"https:\/\/www.kendalmint.co.uk\/cart\/54853515805054:1,56829326164350:1\" title=\"Add Cycle Pack + Upgrade\"\u003e\u003cstrong\u003eAdd Blue Bottle + Upgrade to Cart\u003c\/strong\u003e\u003c\/a\u003e\u003cbr\u003e\u003ca href=\"https:\/\/www.kendalmint.co.uk\/cart\/54853515837822:1,56829326164350:1\" title=\"Add Cycle Pack + Upgrade\"\u003e\u003cstrong\u003eAdd Black Bottle + Upgrade to Cart\u003c\/strong\u003e\u003c\/a\u003e\u003cbr\u003e\u003cem\u003e\u003cbr\u003e*Includes 1 of each item listed. While stocks last.*\u003c\/em\u003e \u003c\/span\u003e \u003cspan style=\"flex: 0 0 auto;\"\u003e \u003ca href=\"https:\/\/www.kendalmint.co.uk\/cart\/43291661959367:1,56829326164350:1\" title=\"Add the upgrade\"\u003e \u003cimg src=\"https:\/\/www.kendalmint.co.uk\/cdn\/shop\/files\/Kendal_Mint_Co_Action_Pack_Add_On.jpg\" alt=\"Kendal Mint Co Action Pack Add-On upgrade\" width=\"110\" height=\"110\" style=\"width: 110px; height: 110px; object-fit: cover; border-radius: 6px; display: block; border: 1px solid #e5e5e5;\"\u003e \u003c\/a\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"\"\u003e\u003cspan class=\"j2store-product-content-field j2store-product-content-field-1\"\u003e\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eItems subject to change, check \"What's included in the pack?\" below.\u003c\/strong\u003e\u003c\/span\u003e\u003c\/div\u003e","brand":"Kendal Mint Co®","offers":[{"title":"Olive Green","offer_id":53230497661256,"sku":"BUN502(GRN)","price":31.86,"currency_code":"GBP","in_stock":true},{"title":"Niagara Blue","offer_id":53230497694024,"sku":"BUN503(BLU)","price":31.86,"currency_code":"GBP","in_stock":true},{"title":"Black","offer_id":53230497726792,"sku":"BUN504(BLK)","price":31.86,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0968\/7603\/6424\/files\/cycle-performance-nutrition-pack-black-kendal-mint-co-bundle-643823.jpg?v=1780565331"},{"product_id":"kmc-nrg-gel-raspberry-mint-energy-gel-70g","title":"KMC NRG GEL Raspberry \u0026 Mint Energy Gel 70g","description":"\u003cp\u003eFuel up quickly and effectively with KMC NRG GEL. Our intelligent Dual Charge Formula™ - A dual-carbohydrate, electrolyte and B vitamin Isotonic formula which provides fast, tasty energy without upsetting your stomach by using Natural Peppermint as an anti-inflammatory. Plus, it's vegan, gluten free, and tested by Informed Sport for athletes' peace of mind. Recharge your Fueling strategy today and choose Nutrition Crafted for Champions. Everest-Tested, Athlete-Approved, built to Conquer Any Challenge, Any Everest. CONQUER YOUR EVEREST.\u003c\/p\u003e","brand":"Kendal Mint Co®","offers":[{"title":"12 x 70g","offer_id":53230497857864,"sku":"GEL411","price":21.24,"currency_code":"GBP","in_stock":true},{"title":"6 x 70g","offer_id":53230497890632,"sku":"GEL401(6)","price":11.68,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0968\/7603\/6424\/files\/Voted_Best_Overall_Gel_Raspberry_1_1_4d042051-6b93-48ed-8cca-e9ef0db111e2.jpg?v=1780565332"},{"product_id":"supplement-needs-heart-stack-formerly-cv-stack","title":"Supplement Needs Heart Stack (Formerly CV Stack)","description":"\u003ch5 data-mce-fragment=\"1\"\u003eLooking to take care of your heart?\u003c\/h5\u003e\n\u003cp data-mce-fragment=\"1\"\u003eHeart Stack is another high spec formulation from the Dr Dean St Mart range!\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eSupplement Needs product formulator Dr Dean St Mart has developed a high quality formula to support heart health and cholesterol metabolism. 11 key ingredients that are fully transparent and effectively dosed that includes the impressive patented vitamin complex EVNol. Just like all the Dr Dean series, zero corners have been cut to deliver one of the best products of its kind!\u003c\/p\u003e","brand":"Supplement Needs","offers":[{"title":"Default Title","offer_id":53230672511304,"sku":"SUNEHESTFOCVST0164","price":54.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0968\/7603\/6424\/files\/NEW-CV-no-sn.jpg?v=1780568223"},{"product_id":"trained-by-jp-hydration","title":"Trained By JP Hydration","description":"\u003cp style=\"text-align: left;\" data-mce-fragment=\"1\" data-mce-style=\"text-align: center;\"\u003e\u003cspan\u003eOur hydration formula is ideal for all sports, levels, ages and genders. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: left;\" data-mce-fragment=\"1\" data-mce-style=\"text-align: center;\"\u003e\u003cspan\u003eIt is designed to be used at any point during training.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: left;\" data-mce-fragment=\"1\" data-mce-style=\"text-align: center;\"\u003e\u003cspan\u003ePre training or pre game - to ensure you go into the session as prepared as possible.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: left;\" data-mce-fragment=\"1\" data-mce-style=\"text-align: center;\"\u003e\u003cspan\u003eDuring training - helps to maintain peak performance.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: left;\" data-mce-fragment=\"1\" data-mce-style=\"text-align: center;\"\u003e\u003cspan\u003eAfter training - to aid in recovery. \u003c\/span\u003e\u003c\/p\u003e","brand":"Trained By JP","offers":[{"title":"Apple \u0026 Melon","offer_id":53230672544072,"sku":"TRBYJPHYAPME1659","price":29.99,"currency_code":"GBP","in_stock":true},{"title":"Pink Lemonade","offer_id":53230672576840,"sku":"TRBYJPHYPILE1660","price":29.99,"currency_code":"GBP","in_stock":true},{"title":"Strawberry Pineapple","offer_id":53230672609608,"sku":"TRBYJPHYSTPI1661","price":29.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0968\/7603\/6424\/files\/Hydro_Melon_Apple_WebImage_1800x1800_png.jpg?v=1780568223"},{"product_id":"per4m-nmn-capsules","title":"Per4m NMN Capsules","description":"\u003ch2 class=\"p1\"\u003e\n\u003cb\u003eNMN support for cellular energy and daily performance\u003c\/b\u003e\u003cb\u003e\u003c\/b\u003e\n\u003c\/h2\u003e\n\u003cp class=\"p1\"\u003eA high strength NMN supplement designed to support cellular energy production, focus and overall wellbeing.\u003c\/p\u003e\n\u003cp class=\"p1\"\u003ePer4m NMN provides 1000mg of Nicotinamide Mononucleotide per serving, a compound involved in the body’s production of NAD⁺, a coenzyme linked to energy metabolism and cellular function. NAD⁺ levels naturally decline over time, which is why NMN is commonly used in routines focused on energy, recovery and long-term health.\u003c\/p\u003e\n\u003cp class=\"p1\"\u003eDelivered in a simple capsule format, it’s designed for easy daily use without the need for mixing or preparation.\u003c\/p\u003e\n\u003ch4 class=\"p1\"\u003e\n\u003cb\u003eProduct highlights\u003c\/b\u003e\u003cb\u003e\u003c\/b\u003e\n\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli class=\"p1\"\u003e1000mg NMN per serving\u003c\/li\u003e\n\u003cli class=\"p1\"\u003eSupports NAD⁺ production\u003c\/li\u003e\n\u003cli class=\"p1\"\u003eDesigned for cellular energy support\u003c\/li\u003e\n\u003cli class=\"p1\"\u003eCapsule format for convenience\u003c\/li\u003e\n\u003cli class=\"p1\"\u003eSuitable for daily use\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4 class=\"p1\"\u003e\n\u003cb\u003eWhat it supports\u003c\/b\u003e\u003cb\u003e\u003c\/b\u003e\n\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli class=\"p1\"\u003eCellular energy production\u003c\/li\u003e\n\u003cli class=\"p1\"\u003eFocus and mental clarity\u003c\/li\u003e\n\u003cli class=\"p1\"\u003eDaily energy levels\u003c\/li\u003e\n\u003cli class=\"p1\"\u003eRecovery and overall wellbeing\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003e\u003cb style=\"font-family: -apple-system, BlinkMacSystemFont, 'San Francisco', 'Segoe UI', Roboto, 'Helvetica Neue', sans-serif; font-size: 0.875rem;\"\u003eWhy Per4m NMN\u003c\/b\u003e\u003c\/h4\u003e\n\u003cp class=\"p1\"\u003eNMN is commonly used to support NAD⁺ levels, which play a key role in how the body produces energy at a cellular level. Maintaining these levels is important for energy metabolism, recovery and general function.\u003c\/p\u003e\n\u003cp class=\"p1\"\u003eThis formula provides a high-strength daily dose in a simple, consistent format.\u003c\/p\u003e\n\u003ch4 class=\"p1\"\u003e\n\u003cb\u003eWho it’s for\u003c\/b\u003e\u003cb\u003e\u003c\/b\u003e\n\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli class=\"p1\"\u003eIndividuals looking to support energy levels\u003c\/li\u003e\n\u003cli class=\"p1\"\u003eThose focused on recovery and performance\u003c\/li\u003e\n\u003cli class=\"p1\"\u003ePeople with demanding schedules\u003c\/li\u003e\n\u003cli class=\"p1\"\u003eAnyone interested in long-term health support\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4 class=\"p1\"\u003e\n\u003cb\u003eKey ingredient\u003c\/b\u003e\u003cb\u003e\u003c\/b\u003e\n\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli class=\"p1\"\u003e\n\u003cb\u003eNMN (Nicotinamide Mononucleotide) - \u003c\/b\u003eA precursor to NAD⁺, involved in cellular energy production and metabolic processes.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4 class=\"p1\"\u003e\n\u003cb\u003eHow to use\u003c\/b\u003e\u003cb\u003e\u003c\/b\u003e\n\u003c\/h4\u003e\n\u003cp class=\"p1\"\u003eTake 2 capsules daily or follow label directions.\u003c\/p\u003e","brand":"Per4m","offers":[{"title":"Default Title","offer_id":53230672478536,"sku":"PENM4010","price":36.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0968\/7603\/6424\/files\/per4m-nmn-60-capsules.webp?v=1780568223"},{"product_id":"now-foods-5-htp","title":"Now Foods 5-HTP","description":"\u003cp\u003e5-HTP, the intermediate metabolite between the amino acid L-tryptophan and serotonin, is extracted from the bean of an African plant (Griffonia simplicifolia).\u003c\/p\u003e","brand":"Now Foods","offers":[{"title":"60 caps","offer_id":53230672642376,"sku":"NOFO5-1371","price":10.99,"currency_code":"GBP","in_stock":false},{"title":"120 caps","offer_id":53230672675144,"sku":"NOFO5-1372","price":18.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0968\/7603\/6424\/files\/now-foods-5-htp-100mg-capsules-60_1.jpg?v=1780568223"},{"product_id":"per4m-plant-protein-900g","title":"Per4m Plant Protein - 900g","description":"\u003cdiv\u003e\n\u003ch5\u003e100% plant sources.\u003c\/h5\u003e\n\u003cp\u003eVegan protein is made completely from plant sourced proteins including pea protein isolate and hemp. 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Elevate your strength game and conquer your fitness goals with the power-packed reliability of Per4m's Liquid Chalk - the essential companion for serious lifters!\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c!----\u003e","brand":"Per4m","offers":[{"title":"Default Title","offer_id":53230692925768,"sku":"PELICH1451","price":9.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0968\/7603\/6424\/files\/LiquidChalk_250ml_5000x_1.jpg?v=1780568627"},{"product_id":"pitstop-fuel-stim-pre-workout","title":"Pitstop+ Fuel (stim pre workout)","description":"\u003cp data-start=\"185\" data-end=\"637\"\u003ePitstop+ Fuel is a high-quality pre-workout formulated to support stronger training sessions through a precise blend of performance-driven ingredients. 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Hawaiian","offer_id":53230697677128,"sku":"APNUABPUREDHAW1135","price":31.99,"currency_code":"GBP","in_stock":true},{"title":"Slush Puppie","offer_id":53230697709896,"sku":"APNUABPUSLPU2280","price":31.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0968\/7603\/6424\/files\/ABEPumpStim-Free500g-Nutritionals-1000x1000_480x480_c02448ab-d0e8-4b15-a8ed-ec0fee15dd70.jpg?v=1780568682"},{"product_id":"pitstop-omega-3","title":"Pitstop+ Omega 3","description":"\u003cp\u003eOmega 3 is an essential fatty acid sourced from fish oil. 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These ingredients are included to help support the body’s natural detoxification processes and protect against oxidative stress.\u003c\/p\u003e\n\u003cp class=\"p1\"\u003eSuitable for consistent daily use, particularly during periods of increased physical stress, higher training load or demanding lifestyles.\u003c\/p\u003e\n\u003ch4 class=\"p1\"\u003e\n\u003cb\u003eProduct highlights\u003c\/b\u003e\u003cb\u003e\u003c\/b\u003e\n\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli class=\"p1\"\u003eIncludes NAC, TUDCA and Glutathione\u003c\/li\u003e\n\u003cli class=\"p1\"\u003eDesigned to support normal liver function\u003c\/li\u003e\n\u003cli class=\"p1\"\u003eProvides antioxidant support\u003c\/li\u003e\n\u003cli class=\"p1\"\u003eHigh-strength, multi-ingredient formula\u003c\/li\u003e\n\u003cli class=\"p1\"\u003eSuitable for daily use\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4 class=\"p1\"\u003e\n\u003cb\u003eWhat it supports\u003c\/b\u003e\u003cb\u003e\u003c\/b\u003e\n\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli class=\"p1\"\u003eNormal liver function\u003c\/li\u003e\n\u003cli class=\"p1\"\u003eAntioxidant defence\u003c\/li\u003e\n\u003cli class=\"p1\"\u003eCellular protection\u003c\/li\u003e\n\u003cli class=\"p1\"\u003eDaily recovery and resilience\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4 class=\"p1\"\u003e\n\u003cb\u003eWhy this formula\u003c\/b\u003e\u003cb\u003e\u003c\/b\u003e\n\u003c\/h4\u003e\n\u003cp class=\"p1\"\u003eThe liver plays a central role in metabolism, detoxification and overall health. This formula combines multiple compounds commonly used to support these processes, rather than relying on a single ingredient.\u003c\/p\u003e\n\u003cp class=\"p1\"\u003eThis approach allows for broader support across liver function and antioxidant protection.\u003c\/p\u003e\n\u003ch4 class=\"p1\"\u003e\n\u003cb\u003eWho it’s for\u003c\/b\u003e\u003cb\u003e\u003c\/b\u003e\n\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli class=\"p1\"\u003eIndividuals training regularly\u003c\/li\u003e\n\u003cli class=\"p1\"\u003eThose with demanding schedules or lifestyles\u003c\/li\u003e\n\u003cli class=\"p1\"\u003ePeople looking to support liver health\u003c\/li\u003e\n\u003cli class=\"p1\"\u003eAnyone focused on long-term health and recovery\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cb\u003eKey ingredients\u003c\/b\u003e\u003cb\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli class=\"p1\"\u003e\n\u003cb\u003eN-Acetyl Cysteine (NAC)\u003c\/b\u003e – supports glutathione production and antioxidant defence\u003c\/li\u003e\n\u003cli class=\"p1\"\u003e\n\u003cb\u003eTUDCA\u003c\/b\u003e – commonly used to support liver function and bile flow\u003c\/li\u003e\n\u003cli class=\"p1\"\u003e\n\u003cb\u003eGlutathione\u003c\/b\u003e – key antioxidant involved in cellular protection\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Per4m","offers":[{"title":"Default Title","offer_id":53230858731848,"sku":"PELISU4019","price":37.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0968\/7603\/6424\/files\/per4m-liver-support-90-capsules.webp?v=1780572917"},{"product_id":"performax-labs-hypermaxd-out","title":"Performax Labs - Hypermax'd Out","description":"\u003cp\u003eIntroducing HyperMax'd Out. 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This completely stacked formula was concocted with all of the meticulous science backed standards that Performax Labs has come to be known for, this time it's just MAX'D OUT!\u003c\/p\u003e\n\u003cp\u003eFueling next level pumps and performance you will find a full 8 gram dose of pure \u003cstrong\u003eL-Citrulline\u003c\/strong\u003e, 3.2 grams of \u003cstrong\u003eBeta Alanine,\u003c\/strong\u003e 2 grams of \u003cstrong\u003eGlycerSize®\u003c\/strong\u003e, 150mg of \u003cstrong\u003eHesperiPump®\u003c\/strong\u003e, 100mg of \u003cstrong\u003ePine Bark Exract\u003c\/strong\u003e, and 200mg of \u003cstrong\u003ePink Himalayan Salt \u003c\/strong\u003emaxing out nitric oxide production, cellular volumization, and over all power output.\u003c\/p\u003e","brand":"Performax labs","offers":[{"title":"Drangon Fruit Mango","offer_id":53230858764616,"sku":"PELA-HYOUDRFR1728","price":40.99,"currency_code":"GBP","in_stock":true},{"title":"Tiger's Blood","offer_id":53230858797384,"sku":"PELA-HYOUTIBL1729","price":40.99,"currency_code":"GBP","in_stock":true},{"title":"Blue Shark Splash","offer_id":53230858830152,"sku":"PELA-HYOUBLSH1731","price":40.99,"currency_code":"GBP","in_stock":true},{"title":"Anaconda Apple","offer_id":53230858862920,"sku":"PELA-HYOUANAP2176","price":40.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0968\/7603\/6424\/files\/performax-labs-hypermaxd-out-616007_500x_0e4bbe4f-05f1-4fc3-aa32-fab0e69eb9ef.jpg?v=1780572917"},{"product_id":"gas-mark-10-locked-in-ultimate-eaas","title":"Gas Mark 10 Locked In Ultimate EAAs","description":"\u003cp class=\"p1\"\u003eLocked In Ultimate EAAs is an intra-workout amino acid formula combining all \u003cspan class=\"s1\"\u003e9 essential amino acids\u003c\/span\u003e with key electrolytes and \u003cspan class=\"s1\"\u003eAstraGin®\u003c\/span\u003e to support muscle recovery, hydration and training performance.\u003c\/p\u003e\n\u003cp class=\"p1\"\u003eDesigned for use during workouts, it helps maintain amino acid availability, support protein synthesis and replenish electrolytes lost through sweat. 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MAX Catalyst® is the gatekeeper that ensures key ingredients reach their destination effectively.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMENACE® V2\u003c\/strong\u003e—More \u003cstrong\u003eENERGY\u003c\/strong\u003e, more \u003cstrong\u003ePUMP\u003c\/strong\u003e, more \u003cstrong\u003eFOCUS\u003c\/strong\u003e, better \u003cstrong\u003eABSORPTION\u003c\/strong\u003e, better \u003cstrong\u003eTASTE\u003c\/strong\u003e, and the \u003cstrong\u003eSAME GREAT PRICE!\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSuggested Use\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-pm-slice=\"1 1 []\"\u003eMix 1 scoop (7g) or 2 scoops (14g) with 200-250ml of water or your preferred beverage. Start with 1 scoop to assess tolerance due to its high stimulant content. 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They are rocking a premium, fully disclosed, 100% whey protein blend (Whey Protein Isolate, Whey Protein Concentrate and Whey Protein Hydrolysate) and a few natural digestives enzymes that have worked best for them, and of course...out of this world flavours. Their protein really is as simple as that. \u003cbr\u003e\u003c\/p\u003e\n\u003ch2\u003eFull Disclosure Label\u003c\/h2\u003e\n\u003cp\u003eAll Ghost products feature a 100% transparent label that fully discloses the dose of each active ingredient. Zero proprietary blends mean you know what you’re getting in each and every scoop. Every scoop of Ghost Whey contains 25g of the purest, fully disclosed whey protein on the market. Flip the tub around and you will find a breakdown of exactly how many grams of whey protein isolate, concentrate and hydrolysate are in every scoop. \u003cbr\u003e\u003c\/p\u003e\n\u003ch2\u003eSoy Free\u003c\/h2\u003e\n\u003cp\u003eWhile most brands use soy lecithinated whey protein, Ghost opted to use only sunflower lecithinated whey protein Why? For starters, Soy is one of the common allergens on the market today. Additionally, soy contains phytoestrogens that mimic the body's natural estrogen hormones, which isn't great for men or women. \u003cbr\u003e\u003c\/p\u003e\n\u003ch2\u003eWhat are the main benefits of Ghost Whey Protein\u003c\/h2\u003e\n\u003cul\u003e\n\u003cul\u003e\n\u003cli\u003eGhost Full Disclosure Label\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cul\u003e\n\u003cli\u003e25g Protein from Whey Protein Isolate, Concentrate and Hydrolysate\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cul\u003e\n\u003cli\u003eVery very nice tasting\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cul\u003e\n\u003cli\u003eGluten Free and Soy Free\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cul\u003e\n\u003cli\u003eLow carb and low fat\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/ul\u003e","brand":"Ghost","offers":[{"title":"Cinnabon","offer_id":53230859649352,"sku":"GHWHPR-92CIN0805","price":39.99,"currency_code":"GBP","in_stock":false},{"title":"Cinnabon Caramel Pecan","offer_id":53230859682120,"sku":"GHWHPR-92CICA1715","price":39.99,"currency_code":"GBP","in_stock":false},{"title":"Chocolate Chip Cookie","offer_id":53230859714888,"sku":"GHWHPR-92CHOCHICOO0806","price":39.99,"currency_code":"GBP","in_stock":true},{"title":"Cinnamon Cereal Milk","offer_id":53230859747656,"sku":"GHWHPR-92CINCERMIL0807","price":39.99,"currency_code":"GBP","in_stock":false},{"title":"Milk Chocolate","offer_id":53230859780424,"sku":"GHWHPR-92MILCHO0808","price":39.99,"currency_code":"GBP","in_stock":true},{"title":"Marshmallow Cereal Milk","offer_id":53230859813192,"sku":"GHWHPR-92MARCERMIL0809","price":39.99,"currency_code":"GBP","in_stock":true},{"title":"Cereal Milk","offer_id":53230859845960,"sku":"GHWHPR-92CERMIL0810","price":39.99,"currency_code":"GBP","in_stock":true},{"title":"Coffee Ice Cream","offer_id":53230859878728,"sku":"GHWHPR-92COFICECRE0811","price":39.99,"currency_code":"GBP","in_stock":true},{"title":"Fruity Cereal Milk","offer_id":53230859911496,"sku":"GHWHPR-92FRUCERMIL0812","price":39.99,"currency_code":"GBP","in_stock":false},{"title":"Peanut Butter Cereal Milk","offer_id":53230859944264,"sku":"GHWHPR-92PEABUTCER0813","price":39.99,"currency_code":"GBP","in_stock":true},{"title":"Strawberry Shortcake","offer_id":53230859977032,"sku":"GHWHPR-92STRSHO0814","price":39.99,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0968\/7603\/6424\/files\/ghost-whey-protein-924g-367882_500x_8d39c55d-71a9-4955-81b1-d00a22e827e2.jpg?v=1780572916"},{"product_id":"engineered-muscle-turbogoline","title":"Engineered Muscle Turbogoline","description":"\u003ch4 class=\"p1\"\u003e\n\u003cb\u003eProlactin \u0026amp; Hormonal Support\u003c\/b\u003e\u003cb\u003e\u003c\/b\u003e\n\u003c\/h4\u003e\n\u003cp class=\"p1\"\u003eEngineered Muscle Turbogoline is a targeted supplement designed to support healthy prolactin levels and overall hormonal balance. 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It’s suitable for use as part of a consistent supplementation routine where hormone regulation and recovery are priorities.\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cb\u003eWhat it supports\u003c\/b\u003e\u003cb\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli class=\"p1\"\u003eHealthy prolactin levels\u003c\/li\u003e\n\u003cli class=\"p1\"\u003eNormal hormone production and metabolism\u003c\/li\u003e\n\u003cli class=\"p1\"\u003eOverall hormonal balance\u003c\/li\u003e\n\u003cli class=\"p1\"\u003eNutrient support for endocrine health\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cb\u003eWho it’s for\u003c\/b\u003e\u003cb\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli class=\"p1\"\u003eIndividuals focused on hormonal balance\u003c\/li\u003e\n\u003cli class=\"p1\"\u003eThose looking to support healthy prolactin levels\u003c\/li\u003e\n\u003cli class=\"p1\"\u003ePerformance-focused lifestyles where recovery and endocrine health matter\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Engineered Muscle","offers":[{"title":"Default Title","offer_id":53230860796232,"sku":"TU2433","price":34.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0968\/7603\/6424\/files\/turbogoline-front.jpg?v=1780572927"},{"product_id":"per4m-plant-protein-2kg","title":"Per4m Plant Protein -2kg","description":"\u003cdiv class=\"station-tabs-tabpanel station-tabs-default-tabpanel is-active\" id=\"station-tabs-tabpanel_ht-i0-t9\" aria-labelledby=\"station-tabs-tab_ht-i0-t9\" aria-hidden=\"false\" role=\"tabpanel\" data-mce-fragment=\"1\"\u003e\n\u003cdiv class=\"station-tabs-tabcontent\" data-mce-fragment=\"1\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003ePER4M Plant Protein now available in both 900g and 2kg.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003ePER4M Plant Protein is made completely from plant sourced proteins. Developed by athletes to support those who follow plant based diets and lifestyle. Consuming essential amino acids and sufficient protein when Plant can be challenging and adding protein to your diet can help support the growth and maintenance of lean muscle mass. Use to increase your daily protein intake or as a base for a delicious and nutritious protein smoothie.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eWe wanted to create a plant based shake that was not only nutritious but also delicious which can be a challenge with plant based protein shakes, but we think we nailed it for you. Each serving delivers a serving of essential amino\u003cbr data-mce-fragment=\"1\"\u003eacids and contains no soya, gluten or lactose.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eUse regularly to increase the protein content of \u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003eyour meals or as a base for a delicious and \u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003enutritious protein smoothie.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"station-tabs-tabcontent\" data-mce-fragment=\"1\"\u003e\n\u003cdiv id=\"stamped-main-widget\" data-product-id=\"8047719710977\" data-name=\"Per4m Plant Protein - 2kg\" data-url=\"https:\/\/insightsupps.com\/products\/per4m-plant-protein-2kg\" data-image-url=\"\/\/insightsupps.com\/cdn\/shop\/products\/per4m-plant-protein-2kg-941257_large.webp%3Fv=1695392801\" data-description='\u0026lt;p data-mce-fragment=\"1\"\u0026gt;\u0026lt;span data-mce-fragment=\"1\"\u0026gt;PER4M Plant Protein now available in both 900g and 2kg.\u0026lt;\/span\u0026gt;\u0026lt;\/p\u0026gt;\n\u0026lt;p data-mce-fragment=\"1\"\u0026gt;\u0026lt;span data-mce-fragment=\"1\"\u0026gt;PER4M Plant Protein is made completely from plant sourced proteins. Developed by athletes to support those who follow plant based diets and lifestyle. Consuming essential amino acids and sufficient protein when Plant can be challenging and adding protein to your diet can help support the growth and maintenance of lean muscle mass. Use to increase your daily protein intake or as a base for a delicious and nutritious protein smoothie.\u0026lt;\/span\u0026gt;\u0026lt;\/p\u0026gt;\n\u0026lt;p data-mce-fragment=\"1\"\u0026gt;\u0026lt;span data-mce-fragment=\"1\"\u0026gt;We wanted to create a plant based shake that was not only nutritious but also delicious which can be a challenge with plant based protein shakes, but we think we nailed it for you. Each serving delivers a serving of essential amino\u0026lt;br data-mce-fragment=\"1\"\u0026gt;acids and contains no soya, gluten or lactose.\u0026lt;\/span\u0026gt;\u0026lt;\/p\u0026gt;\n\u0026lt;p data-mce-fragment=\"1\"\u0026gt;\u0026lt;span data-mce-fragment=\"1\"\u0026gt;Use regularly to increase the protein content of \u0026lt;\/span\u0026gt;\u0026lt;span data-mce-fragment=\"1\"\u0026gt;your meals or as a base for a delicious and \u0026lt;\/span\u0026gt;\u0026lt;span data-mce-fragment=\"1\"\u0026gt;nutritious protein smoothie.\u0026lt;\/span\u0026gt;\u0026lt;\/p\u0026gt;' data-product-sku=\"per4m-plant-protein-2kg\" data-product-type=\"\" class=\"\" data-mce-fragment=\"1\"\u003e\n\u003cdiv class=\"stamped-container\" data-count=\"0\" data-widget-style=\"standard2\" data-widget-sort=\"recent\" data-widget-language=\"en\" data-widget-show-graph=\"true\" data-widget-show-summary-photo=\"true\" data-widget-show-sort=\"true\" data-widget-show-summary-recommend=\"true\" data-widget-show-tab-reviews=\"true\" data-widget-show-avatar=\"true\" data-widget-show-location=\"true\" data-widget-show-verified=\"true\" data-widget-show-date=\"true\" data-widget-show-share=\"true\" data-widget-show-votes=\"true\" data-widget-show-qna=\"true\" data-widget-show-product-variant=\"true\" data-widget-show-filter-custom-forms=\"true\" data-widget-show-filter-search=\"true\" data-widget-type=\"standard2\" data-widget-show-smart-guide=\"true\" data-version=\"2\" data-mce-fragment=\"1\"\u003e\n\u003cdiv class=\"stamped-content\" data-mce-fragment=\"1\"\u003e\n\u003cdiv class=\"stamped-messages\" data-mce-fragment=\"1\"\u003e\n\u003cdiv class=\"stamped-empty-state\" style=\"display: none;\" data-mce-fragment=\"1\" data-mce-style=\"display: none;\"\u003e\n\u003cdiv data-mce-fragment=\"1\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Per4m","offers":[{"title":"Strawberry creme","offer_id":53230860829000,"sku":"PEPLPR-2STRCRE1150","price":44.99,"currency_code":"GBP","in_stock":true},{"title":"Raspberry White Chocolate","offer_id":53230860861768,"sku":"PEPLPR-2RASWHICHO1151","price":44.99,"currency_code":"GBP","in_stock":false},{"title":"Double Chocolate","offer_id":53230860894536,"sku":"PEPLPR-2DOUCHO1152","price":44.99,"currency_code":"GBP","in_stock":true},{"title":"Vanilla Creme","offer_id":53230860927304,"sku":"PEPLPR-2VANCRE1153","price":44.99,"currency_code":"GBP","in_stock":true},{"title":"Choconut","offer_id":53230860960072,"sku":"PEPLPR-2CHO1154","price":44.99,"currency_code":"GBP","in_stock":false},{"title":"Choc Orange","offer_id":53230860992840,"sku":"PEPLPR-2CHOORA1155","price":44.99,"currency_code":"GBP","in_stock":true},{"title":"Choc Mint","offer_id":53230861025608,"sku":"PEPLPR-2CHOMIN1156","price":44.99,"currency_code":"GBP","in_stock":true},{"title":"Salted Caramel","offer_id":53230861058376,"sku":"PEPLPR-2SALCAR1157","price":44.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0968\/7603\/6424\/files\/per4m-plant-protein-2kg-941257_500x_991c73e8-2366-48f4-8ad9-91f4f29ee769.jpg?v=1780572926"},{"product_id":"combat-fuel-clear-whey-490g","title":"Combat fuel Clear Whey - 490g","description":"\u003ch6 data-mce-fragment=\"1\"\u003eCLEAR WHEY PROTEIN – NON-MILKY, REFRESHING JUICE LIKE PROTEIN SHAKE\u003c\/h6\u003e\n\u003cp data-mce-fragment=\"1\"\u003eOur Clear Whey Protein isn’t just another protein shake. We get it, as delicious as our Premium Whey Protein is, sometimes something refreshing is a better alternative. So we took extremely high-quality hydrolysed whey protein and created a light, thirst-quenching, refreshing alternative that’s more like juice than a heavy sitting milky protein shake!\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eWhat’s more unlike any other clear whey protein on the market ours contains AstraGin® to aid absorption giving you the best bang for your buck!\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eAvailable in four incredible flavours!\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e490g, 20 servings per tub.\u003c\/p\u003e\n\u003ch6 data-mce-fragment=\"1\"\u003eWHEN SHOULD I TAKE IT AND HOW MUCH?\u003c\/h6\u003e\n\u003cp data-mce-fragment=\"1\"\u003eCombat Fuel’s Clear Whey Protein is fast-absorbing, making it ideal post-workout; however, it can be taken at any time. How many protein shakes a day? Try not to worry about the number of shakes a day – instead, aim for 1.5-2g of protein per kg of lean body weight daily. This is a perfect way to refreshingly supplement your diet, helping you hit your individual daily protein goals.\u003c\/p\u003e\n\u003ch6 data-mce-fragment=\"1\"\u003eWHY COMBAT FUEL?\u003c\/h6\u003e\n\u003cul data-mce-fragment=\"1\"\u003e\n\u003cli data-mce-fragment=\"1\"\u003eHigh protein content!\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003eAstragin for absorption!\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003eNo fillers!\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003eSuperior mixability!\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003eIt’s not spiked with aminos!\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003e20.1g \u003ca href=\"https:\/\/cf.dev2.fhoke.com\/protein\/\" data-mce-fragment=\"1\"\u003eprotein\u003c\/a\u003e per scoop!\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003eOnly 83Kcal per scoop!\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Combat Fuel","offers":[{"title":"Blue Razz","offer_id":53230861091144,"sku":"COFUCLWH-49BLURAZ0673","price":29.99,"currency_code":"GBP","in_stock":true},{"title":"Iron Brew","offer_id":53230861123912,"sku":"COFUCLWH-49IROBRE0674","price":29.99,"currency_code":"GBP","in_stock":true},{"title":"Unicorn Piss","offer_id":53230861156680,"sku":"COFUCLWH-49UNIPIS0675","price":29.99,"currency_code":"GBP","in_stock":true},{"title":"Cloudy Lemonade","offer_id":53230861189448,"sku":"COFUCLWH-49CLOLEM0676","price":29.99,"currency_code":"GBP","in_stock":true},{"title":"Spinegrapple","offer_id":53230861222216,"sku":"COFUCLWH-49SPI0677","price":29.99,"currency_code":"GBP","in_stock":true},{"title":"Candy Bits","offer_id":53230861254984,"sku":"COFUCLWH-49CANBIT0678","price":29.99,"currency_code":"GBP","in_stock":true},{"title":"Watermelon","offer_id":53230861287752,"sku":"COFUCLWH-49WAT0679","price":29.99,"currency_code":"GBP","in_stock":true},{"title":"Strawberry \u0026 Lime","offer_id":53230861320520,"sku":"COFUCLWH-49STRLIM0680","price":29.99,"currency_code":"GBP","in_stock":true},{"title":"Cola","offer_id":53230861353288,"sku":"COFUCLWH-49COL0681","price":29.99,"currency_code":"GBP","in_stock":true},{"title":"Cherry","offer_id":53230861386056,"sku":"COFUCLWH-49CH2043","price":29.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0968\/7603\/6424\/files\/CF-Clear-Whey-Cola-Front-796x796.jpg?v=1780572926"},{"product_id":"unrivalled-rapid-recovery-tasting-tub-320g","title":"Unrivalled Rapid Recovery Tasting Tub- 320g","description":"\u003ch5 data-mce-fragment=\"1\"\u003eRAPID RECOVERY is a scientifically superior formula of super fast acting carbohydrates and amino rich glycogenic proteins.\u003c\/h5\u003e\n\u003cp data-mce-fragment=\"1\"\u003eRAPID RECOVERY is specifically formulated to facilitate Rapid Recovery from any strenuous exercise. Unrivalled Rapid Recovery has the optimal amount of high glycemic carbohydrates and superior fast acting proteins in the recommended scientific ratios. Our unique formula is the perfect post-workout solution as it kick starts the whole Recovery, repair and growth process. Rapid Recovery helps utilise this critical window of opportunity.\u003c\/p\u003e","brand":"Unrivalled","offers":[{"title":"Choccy biscuit","offer_id":53230861418824,"sku":"UNRARETATU32CHOBIS1217","price":9.99,"currency_code":"GBP","in_stock":true},{"title":"Wild Raspberry","offer_id":53230861451592,"sku":"UNRARETATU32WILRAS1218","price":9.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0968\/7603\/6424\/files\/rr_320g_wild_rasp-1_1.jpg?v=1780572927"},{"product_id":"now-foods-maca-500mg","title":"Now Foods Maca 500mg","description":null,"brand":"Now Foods","offers":[{"title":"100 Caps","offer_id":53230861484360,"sku":"NOFOMA50-10CA0555","price":9.99,"currency_code":"GBP","in_stock":false},{"title":"250 Caps","offer_id":53230861517128,"sku":"NOFOMA5025CA2486","price":18.49,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0968\/7603\/6424\/files\/27.jpg?v=1780572927"},{"product_id":"per4m-relax-hot-chocolate","title":"Per4m Relax Hot Chocolate","description":"\u003cp\u003e\u003cspan style=\"font-size: 1rem;\"\u003ePER4M RELAX Hot Chocolate is your new go-to for winding down and managing stress, combining indulgence with wellness in every sip. 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Whether you're curling up with a book or easing into sleep, PER4M RELAX Hot Chocolate is the ultimate companion for your nighttime routine.\u003c\/p\u003e","brand":"Per4m","offers":[{"title":"Default Title","offer_id":53230861549896,"sku":"PEREHOCH1598","price":29.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0968\/7603\/6424\/files\/relax-hot-chocolate_1.jpg?v=1780572927"},{"product_id":"per4m-shaker","title":"Per4m Shaker","description":"PER4M Multifunctional 700ml shaker ideal for mixing pre, intra and post shakes or when you are on the go.","brand":"Per4m","offers":[{"title":"Clear","offer_id":53230863286600,"sku":"PESHCLE1336","price":4.99,"currency_code":"GBP","in_stock":true},{"title":"White","offer_id":53230863319368,"sku":"PESHWHI1337","price":4.99,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0968\/7603\/6424\/files\/per4mshaker_white_2000x_8315395a-0544-448a-a201-4d37be966d6b.jpg?v=1780572952"},{"product_id":"gorilla-alpha-ibiza-juice-ultimate-energy","title":"Gorilla Alpha Ibiza Juice ULTIMATE ENERGY","description":"\u003cdiv class=\"station-tabs-tabpanel station-tabs-default-tabpanel is-active\" id=\"station-tabs-tabpanel_ht-i0-t41\" aria-labelledby=\"station-tabs-tab_ht-i0-t41\" aria-hidden=\"false\" role=\"tabpanel\" data-mce-fragment=\"1\"\u003e\n\u003cdiv class=\"station-tabs-tabcontent\" data-mce-fragment=\"1\"\u003e\n\u003cspan data-mce-fragment=\"1\"\u003eStart Your Workouts STRONG Drink NEW Ibiza Juice ULTIMATE energy Vol.1\u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eFor the ULTIMATE WORKOUT and TASTE Experience, It Will Take It to The MAX 🤘🏼\u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eFeaturing 7 Trademarked ingredients that cover…\u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e🔥Energy\u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e🔥Powerful Nootropics\u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e🔥Mood elevation and muscle control, or better known as the mind-muscle connection.\u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e🔥Improved cognitive function\u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e🔥Hydration\u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e🔥Absorption\u003c\/span\u003e\u003cbr\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Gorillalpha","offers":[{"title":"Ultimate Bubblegum Popsicle","offer_id":53230863352136,"sku":"GOALIBJUULENULTBUBPOP1136","price":37.99,"currency_code":"GBP","in_stock":true},{"title":"Grape Strawberry Orange Slushie","offer_id":53230863384904,"sku":"GOALIBJUULENGRASTRORA1137","price":37.99,"currency_code":"GBP","in_stock":true},{"title":"LuvdUp","offer_id":53230863417672,"sku":"GOALIBJUULENLUV1138","price":37.99,"currency_code":"GBP","in_stock":true},{"title":"Ultimate Sherbert Double Dipped","offer_id":53230863450440,"sku":"GOALIBJUULENULTSHEDOU1139","price":37.99,"currency_code":"GBP","in_stock":true},{"title":"Ultimate Twister Lollypop","offer_id":53230863483208,"sku":"GOALIBJUULENULTTWILOL1140","price":37.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0968\/7603\/6424\/files\/gorillalpha-ibiza-juice-ultimate-energy-vol1-171689_500x_bb5bb20c-2f35-47ad-9f7b-ec553a430140.jpg?v=1780572952"},{"product_id":"cretan-gaia-cannabis-honey-extract-1000mg-cbd-for-face-mask-100ml","title":"Cretan Gaia Cannabis Honey Extract – 1000mg CBD, for Face Mask, 100ml","description":"\u003cdiv data-widget_type=\"heading.default\" data-element_type=\"widget\" data-id=\"401ec086\" class=\"elementor-element elementor-element-401ec086 elementor-widget elementor-widget-heading\"\u003e\n\u003cdiv class=\"elementor-widget-container\"\u003e\n\u003cp data-start=\"66\" data-end=\"167\"\u003e\u003cstrong data-start=\"66\" data-end=\"107\"\u003eCretan Gaia CBD Honey Extract – 1000mg CBD \/ 100ml\u003c\/strong\u003e\u003cbr data-start=\"107\" data-end=\"110\"\u003e\u003cstrong\u003eThe power of honey and CBD for a clean and radiant face\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-start=\"169\" data-end=\"656\"\u003eA pure facial cleansing mask with only two ingredients: organic honey and pure cannabidiol (CBD). With a 100% natural formula and free from chemical additives, preservatives, or surfactants, it provides gentle yet deep care. Honey moisturizes and nourishes the skin, leaving it soft and smooth, while CBD acts as a powerful antioxidant, strengthening the skin barrier and revitalizing the complexion. The synergy of honey and CBD delivers natural radiance and rejuvenation to the face.\u003c\/p\u003e\n\u003chr data-start=\"658\" data-end=\"661\"\u003e\n\u003ch3 data-start=\"663\" data-end=\"677\"\u003eFeatures\u003c\/h3\u003e\n\u003cul data-start=\"678\" data-end=\"1184\"\u003e\n\u003cli data-start=\"678\" data-end=\"766\"\u003e\n\u003cp data-start=\"680\" data-end=\"766\"\u003e\u003cstrong data-start=\"680\" data-end=\"710\"\u003eMoisturizing \u0026amp; Nourishing:\u003c\/strong\u003e Honey acts as a natural humectant, leaving skin soft.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"767\" data-end=\"856\"\u003e\n\u003cp data-start=\"769\" data-end=\"856\"\u003e\u003cstrong data-start=\"769\" data-end=\"782\"\u003eSoothing:\u003c\/strong\u003e Helps calm occasional irritation and gives the skin a comfortable feel.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"857\" data-end=\"1015\"\u003e\n\u003cp data-start=\"859\" data-end=\"1015\"\u003e\u003cstrong data-start=\"859\" data-end=\"886\"\u003eAntioxidant Protection:\u003c\/strong\u003e CBD and honey serve as natural antioxidants, helping protect the skin from environmental stressors (pollution, free radicals).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"1016\" data-end=\"1123\"\u003e\n\u003cp data-start=\"1018\" data-end=\"1123\"\u003e\u003cstrong data-start=\"1018\" data-end=\"1035\"\u003eRevitalizing:\u003c\/strong\u003e Refreshes the skin and enhances its natural radiance, leaving the complexion healthy.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"1124\" data-end=\"1184\"\u003e\n\u003cp data-start=\"1126\" data-end=\"1184\"\u003e\u003cstrong data-start=\"1126\" data-end=\"1145\"\u003eMade in Greece:\u003c\/strong\u003e Produced with certified ingredients.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-start=\"1186\" data-end=\"1189\"\u003e\n\u003ch3 data-start=\"1191\" data-end=\"1207\"\u003eDirections\u003c\/h3\u003e\n\u003cp data-start=\"1208\" data-end=\"1310\"\u003eApply evenly to clean, dry face. Leave on for 15 minutes, then rinse thoroughly with lukewarm water.\u003c\/p\u003e\n\u003chr data-start=\"1312\" data-end=\"1315\"\u003e\n\u003ch3 data-start=\"1317\" data-end=\"1331\"\u003eWarnings\u003c\/h3\u003e\n\u003cp data-start=\"1332\" data-end=\"1590\"\u003eFor external use only. Avoid contact with eyes – in case of contact, rinse thoroughly with water. Fragrance-free to minimize irritation. If sensitivity occurs (e.g., honey allergy), discontinue use. Keep out of reach of children. Store at room temperature.\u003c\/p\u003e\n\u003chr data-start=\"1592\" data-end=\"1595\"\u003e\n\u003ch3 data-start=\"1597\" data-end=\"1618\"\u003eAdditional Info\u003c\/h3\u003e\n\u003cul data-start=\"1619\" data-end=\"1871\"\u003e\n\u003cli data-start=\"1619\" data-end=\"1704\"\u003e\n\u003cp data-start=\"1621\" data-end=\"1704\"\u003e\u003cstrong data-start=\"1621\" data-end=\"1643\"\u003eCrystal Formation:\u003c\/strong\u003e A natural phenomenon that does not affect product quality.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"1705\" data-end=\"1768\"\u003e\n\u003cp data-start=\"1707\" data-end=\"1768\"\u003e\u003cstrong data-start=\"1707\" data-end=\"1722\"\u003eShelf Life:\u003c\/strong\u003e 3 years unopened \/ 12 months after opening.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"1769\" data-end=\"1871\"\u003e\n\u003cp data-start=\"1771\" data-end=\"1871\"\u003e\u003cstrong data-start=\"1771\" data-end=\"1786\"\u003eLab-Tested:\u003c\/strong\u003e Includes cannabinoid profile, heavy metals, pesticides \u0026amp; solvent residue analysis.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"CRETAN GAIA PRODUCTS","offers":[{"title":"Default Title","offer_id":53231331049800,"sku":"4880312","price":30.27,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0968\/7603\/6424\/files\/ChatGPT_Image_12_2025_07_08_26_._..png?v=1780577081"},{"product_id":"natura-inside-premium-cannabis-oil-7-cbd-with-piperine-coffee-oil-dryas-series-10ml","title":"Natura Inside Premium Cannabis Oil – 7% CBD with Piperine \u0026 Coffee Oil, Dryas Series, 10ml","description":"\u003cp data-end=\"522\" data-start=\"427\"\u003e\u003cstrong data-end=\"478\" data-start=\"427\"\u003eCBD Coffee Drops with Piperine\u003c\/strong\u003e\u003cbr data-end=\"481\" data-start=\"478\"\u003e\u003cstrong data-end=\"520\" data-start=\"481\"\u003eNatural Synergy for Daily Premium Care\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-end=\"809\" data-start=\"524\"\u003e\u003cstrong data-end=\"542\" data-start=\"524\"\u003eDryas\u003c\/strong\u003e is crafted with CBD, cold-pressed Arabica coffee seed oil, and piperine, offering a plant-based formulation that can be easily integrated into daily routines. The blend combines full extract CBD with natural oils, designed to support a balanced lifestyle.\u003c\/p\u003e\n\u003ch3 data-end=\"825\" data-start=\"811\"\u003eFeatures\u003c\/h3\u003e\n\u003cul data-end=\"1187\" data-start=\"826\"\u003e\n\u003cli data-end=\"866\" data-start=\"826\"\u003e\n\u003cp data-end=\"866\" data-start=\"828\"\u003e\u003cstrong data-end=\"843\" data-start=\"828\"\u003eCBD Content\u003c\/strong\u003e: 7% (700mg per 10ml)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-end=\"936\" data-start=\"867\"\u003e\n\u003cp data-end=\"936\" data-start=\"869\"\u003e\u003cstrong data-end=\"886\" data-start=\"869\"\u003eWith Piperine\u003c\/strong\u003e: Included to support ingredient bioavailability\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-end=\"1021\" data-start=\"937\"\u003e\n\u003cp data-end=\"1021\" data-start=\"939\"\u003e\u003cstrong data-end=\"971\" data-start=\"939\"\u003eCold-Pressed Coffee Seed Oil\u003c\/strong\u003e: Adds a natural touch from Arabica coffee seeds\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-end=\"1187\" data-start=\"1118\"\u003e\n\u003cp data-end=\"1187\" data-start=\"1120\"\u003e\u003cstrong data-end=\"1135\" data-start=\"1120\"\u003ePlant-Based\u003c\/strong\u003e: Made with carefully selected natural ingredients\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e🧪 \u003cstrong data-end=\"113\" data-start=\"99\"\u003eHow to Use\u003c\/strong\u003e\u003cbr data-end=\"116\" data-start=\"113\"\u003e• Shake well before use\u003cbr data-end=\"142\" data-start=\"139\"\u003e• Apply a small amount 2–3 times daily, preferably every day\u003cbr data-end=\"283\" data-start=\"280\"\u003e• Store in a cool, dark place at room temperature (15–25 °C)\u003c\/p\u003e\n\u003cp data-end=\"243\" data-start=\"98\"\u003e\u003cem data-end=\"241\" data-start=\"121\"\u003eWant to learn more about cannabidiol \u0026amp; coffee oil? Check out this short blog.\u003c\/em\u003e\u003c\/p\u003e\n\u003chr\u003e\n\u003ch3\u003e🧬 \u003cstrong\u003eCannabidiol (CBD) and Scientifically Documented Properties\u003c\/strong\u003e\n\u003c\/h3\u003e\n\u003cp\u003eCannabidiol (CBD) is a natural phytocannabinoid derived from the \u003cem\u003eCannabis sativa\u003c\/em\u003e plant. Unlike tetrahydrocannabinol (THC), CBD is \u003cstrong\u003enon-psychoactive\u003c\/strong\u003e, making it safe for daily use¹. It interacts with the \u003cstrong\u003eendocannabinoid system (ECS)\u003c\/strong\u003e, which regulates key physiological functions such as anxiety, pain, sleep, and immune balance².\u003c\/p\u003e\n\u003chr\u003e\n\u003cp\u003e📌 \u003cstrong\u003eKey Properties Identified in Scientific Literature:\u003c\/strong\u003e\u003cbr\u003e• \u003cstrong\u003eAnxiety and stress relief\u003c\/strong\u003e: CBD appears to interact with serotonin receptors, contributing to anxiolytic effects³. It has been studied in cases of social anxiety, generalized anxiety disorder, and PTSD.\u003cbr\u003e• \u003cstrong\u003eSleep support\u003c\/strong\u003e: Research shows that CBD may improve sleep quality and duration, particularly when sleep disturbances are related to anxiety⁴.\u003cbr\u003e• \u003cstrong\u003eAnti-inflammatory and analgesic properties\u003c\/strong\u003e: CBD influences CB1, CB2, and TRPV1 receptors, supporting relief from chronic or neuropathic pain and reducing inflammation⁵.\u003cbr\u003e• \u003cstrong\u003ePhysiological balance (homeostasis)\u003c\/strong\u003e: By modulating the ECS, CBD may help support general wellbeing and internal balance⁶.\u003cbr\u003e• \u003cstrong\u003eAntioxidant and immunomodulatory effects\u003c\/strong\u003e: Experimental data suggest CBD may reduce pro-inflammatory cytokines and support immune response⁷.\u003cstrong\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences\u003c\/strong\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cp\u003eWorld Health Organization. (2018). \u003cem\u003eCannabidiol (CBD) Critical Review Report\u003c\/em\u003e.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eLowe, H. I. C., Toyang, N. J., \u0026amp; McLaughlin, W. (2021). \u003cem\u003eMedicines\u003c\/em\u003e, 8(6), 44. \u003ca href=\"https:\/\/doi.org\/10.3390\/molecules26237216\"\u003ehttps:\/\/doi.org\/10.3390\/medicines8060044\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eBlessing, E. M., et al. (2015). \u003cem\u003eNeurotherapeutics\u003c\/em\u003e, 12(4), 825–836. \u003ca href=\"https:\/\/doi.org\/10.1007\/s13311-015-0387-1\"\u003ehttps:\/\/doi.org\/10.1007\/s13311-015-0387-1\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eShannon, S., et al. (2019). \u003cem\u003eThe Permanente Journal\u003c\/em\u003e, 23. \u003ca href=\"https:\/\/doi.org\/10.7812\/TPP\/18-041\"\u003ehttps:\/\/doi.org\/10.7812\/TPP\/18-041\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eWhiting, P. F., et al. (2015). \u003cem\u003eJAMA\u003c\/em\u003e, 313(24), 2456–2473. \u003ca href=\"https:\/\/doi.org\/10.1001\/jama.2015.6358\"\u003ehttps:\/\/doi.org\/10.1001\/jama.2015.6358\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eNichols, J. M., \u0026amp; Kaplan, B. L. (2020). \u003cem\u003eCannabis and Cannabinoid Research\u003c\/em\u003e, 5(1), 12–31. \u003ca href=\"https:\/\/doi.org\/10.1089\/can.2018.0073\"\u003ehttps:\/\/doi.org\/10.1089\/can.2018.0073\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eKozela, E., et al. (2011). \u003cem\u003eJournal of Neuroimmune Pharmacology\u003c\/em\u003e, 6(3), 529–540. \u003ca class=\"epub-doi\" aria-label=\"Digital Object Identifier for Cannabidiol inhibits pathogenic T cells, decreases spinal microglial activation and ameliorates multiple sclerosis-like disease in C57BL\/6 mice link\" href=\"https:\/\/doi.org\/10.1111\/j.1476-5381.2011.01379.x\"\u003ehttps:\/\/doi.org\/10.1111\/j.1476-5381.2011.01379.x\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eStahl, V., \u0026amp; Vasudevan, K. (2020). \u003cem\u003eCureus\u003c\/em\u003e, 12(1), e6809. \u003ca href=\"https:\/\/doi.org\/10.7759\/cureus.6809\"\u003ehttps:\/\/doi.org\/10.7759\/cureus.6809\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eIffland, K., \u0026amp; Grotenhermen, F. (2017). \u003cem\u003eCannabis and Cannabinoid Research\u003c\/em\u003e, 2(1), 139–154. \u003ca href=\"https:\/\/doi.org\/10.1089\/can.2016.0034\"\u003ehttps:\/\/doi.org\/10.1089\/can.2016.0034\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eRegulation (EU) No 1307\/2013 and Directive 2002\/46\/EC – \u003cstrong\u003eEU compliance on hemp and novel foods\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch3 data-start=\"0\" data-end=\"81\"\u003e☕ Coffee Oil: A Multifunctional Bioactive for Skin Health and Inner Balance\u003c\/h3\u003e\n\u003cp data-start=\"83\" data-end=\"857\"\u003eCoffee oil, obtained through the cold pressing of green or roasted coffee beans, is a \u003cstrong data-start=\"169\" data-end=\"195\"\u003ebioactive-rich extract\u003c\/strong\u003e containing \u003cstrong data-start=\"207\" data-end=\"297\"\u003editerpenes (cafestol, kahweol), tocopherols (vitamin E), phytosterols, and polyphenols\u003c\/strong\u003e. These compounds offer \u003cstrong data-start=\"321\" data-end=\"338\"\u003edual benefits\u003c\/strong\u003e for both \u003cstrong data-start=\"348\" data-end=\"371\"\u003etopical (skin care)\u003c\/strong\u003e and \u003cstrong data-start=\"376\" data-end=\"402\"\u003esystemic (nutritional)\u003c\/strong\u003e applications. When used on the skin, coffee oil exhibits \u003cstrong data-start=\"460\" data-end=\"512\"\u003eantioxidant, anti-inflammatory, and revitalizing\u003c\/strong\u003e properties—helping to \u003cstrong data-start=\"535\" data-end=\"571\"\u003eprotect against oxidative stress\u003c\/strong\u003e, \u003cstrong data-start=\"573\" data-end=\"595\"\u003eimprove elasticity\u003c\/strong\u003e, and \u003cstrong data-start=\"601\" data-end=\"629\"\u003esupport the skin barrier\u003c\/strong\u003e. Its \u003cstrong data-start=\"635\" data-end=\"660\"\u003eessential fatty acids\u003c\/strong\u003e contribute to \u003cstrong data-start=\"675\" data-end=\"703\"\u003ehydration and smoothness\u003c\/strong\u003e, while \u003cstrong data-start=\"711\" data-end=\"738\"\u003ecaffeine and diterpenes\u003c\/strong\u003e help \u003cstrong data-start=\"744\" data-end=\"774\"\u003estimulate microcirculation\u003c\/strong\u003e, enhancing skin tone and radiance (Dourado et al., 2020; Herman \u0026amp; Herman, 2013).\u003c\/p\u003e\n\u003cp data-start=\"859\" data-end=\"1580\"\u003eWhen taken as a supplement, the same bioactive molecules act internally to \u003cstrong data-start=\"934\" data-end=\"973\"\u003eprotect cells from oxidative damage\u003c\/strong\u003e, \u003cstrong data-start=\"975\" data-end=\"1007\"\u003esupport liver detoxification\u003c\/strong\u003e, and \u003cstrong data-start=\"1013\" data-end=\"1038\"\u003epromote lipid balance\u003c\/strong\u003e. Diterpenes such as \u003cstrong data-start=\"1059\" data-end=\"1083\"\u003ecafestol and kahweol\u003c\/strong\u003e activate \u003cstrong data-start=\"1093\" data-end=\"1125\"\u003ephase II detoxifying enzymes\u003c\/strong\u003e and \u003cstrong data-start=\"1130\" data-end=\"1155\"\u003eglutathione synthesis\u003c\/strong\u003e, reinforcing liver function (Cavin et al., 2002). Meanwhile, \u003cstrong data-start=\"1217\" data-end=\"1233\"\u003ephytosterols\u003c\/strong\u003e like \u003cstrong data-start=\"1239\" data-end=\"1255\"\u003eβ-sitosterol\u003c\/strong\u003e and \u003cstrong data-start=\"1260\" data-end=\"1276\"\u003estigmasterol\u003c\/strong\u003e assist in \u003cstrong data-start=\"1287\" data-end=\"1313\"\u003echolesterol regulation\u003c\/strong\u003e and cardiovascular support (Godos et al., 2014). Overall, coffee oil represents a \u003cstrong data-start=\"1396\" data-end=\"1432\"\u003esynergistic botanical ingredient\u003c\/strong\u003e that supports \u003cstrong data-start=\"1447\" data-end=\"1510\"\u003eskin vitality, cellular protection, and systemic well-being\u003c\/strong\u003e, bridging the connection between \u003cstrong data-start=\"1544\" data-end=\"1577\"\u003eouter beauty and inner health\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cp data-start=\"1587\" data-end=\"1610\"\u003e\u003cstrong data-start=\"1587\" data-end=\"1608\"\u003eReferences:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul data-start=\"1611\" data-end=\"2399\"\u003e\n\u003cli data-start=\"1611\" data-end=\"1841\"\u003e\n\u003cp data-start=\"1613\" data-end=\"1841\"\u003eCavin, C., Holzhaeuser, D., Scharf, G., Constable, A., Huber, W. W., \u0026amp; Schilter, B. (2002). Cafestol and kahweol, two coffee-specific diterpenes with anticarcinogenic activity. \u003cem data-start=\"1790\" data-end=\"1824\"\u003eFood and Chemical Toxicology, 40\u003c\/em\u003e(8), 1155–1163.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"1842\" data-end=\"2020\"\u003e\n\u003cp data-start=\"1844\" data-end=\"2020\"\u003eDourado, G. K. Z. S., de Souza, A. L. R., \u0026amp; dos Santos, P. O. (2020). Coffee oil as an ingredient in cosmetics: A review. \u003cem data-start=\"1966\" data-end=\"2003\"\u003eJournal of Cosmetic Dermatology, 19\u003c\/em\u003e(9), 2407–2414.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"2021\" data-end=\"2256\"\u003e\n\u003cp data-start=\"2023\" data-end=\"2256\"\u003eGodos, J., Pluchinotta, F. R., Marventano, S., Buscemi, S., Li Volti, G., Galvano, F., \u0026amp; Grosso, G. (2014). Coffee components and cardiovascular risk: Beneficial and detrimental effects. \u003cem data-start=\"2210\" data-end=\"2239\"\u003ePublic Health Nutrition, 17\u003c\/em\u003e(9), 2073–2089.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"2257\" data-end=\"2399\"\u003e\n\u003cp data-start=\"2259\" data-end=\"2399\"\u003eHerman, A., \u0026amp; Herman, A. P. (2013). Caffeine’s mechanisms of action and its cosmetic use. \u003cem data-start=\"2349\" data-end=\"2387\"\u003eSkin Pharmacology and Physiology, 26\u003c\/em\u003e(1), 8–14.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eNote:\u003c\/strong\u003e This product is registered in the European CPNP database with \u003cstrong\u003eNotification Number: CPNP 4619441\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cp\u003eThe information presented is based on published scientific literature regarding \u003cb\u003ethe compounds\u003c\/b\u003e and \u003cstrong\u003edoes not constitute a health claim\u003c\/strong\u003e for the final product. This product is \u003cstrong\u003enot intended to diagnose, treat, cure, or prevent any disease\u003c\/strong\u003e.\u003c\/p\u003e","brand":"Natura Inside","offers":[{"title":"Default Title","offer_id":53231330951496,"sku":"LA2907","price":11.23,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0968\/7603\/6424\/files\/coffee_NewForm.jpg?v=1780577080"},{"product_id":"cretan-gaia-full-extract-cannabis-oil-5-cbg-10ml","title":"Cretan Gaia Full Extract Cannabis Oil – 5% CBG, 10ml","description":"\u003cp data-start=\"321\" data-end=\"368\"\u003e\u003cstrong data-start=\"321\" data-end=\"366\"\u003eCRETAN GAIA Full Extract CBG Oil 5%, 10ml\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-start=\"370\" data-end=\"695\"\u003eThe \u003cstrong data-start=\"374\" data-end=\"410\"\u003eCRETAN GAIA Full Extract CBG Oil\u003c\/strong\u003e is carefully crafted from Cretan hemp flowers and blended with natural oils for a rich, plant-based composition. The full spectrum formula contains only full extract, natural terpenes, and plant material, offering a holistic approach designed to complement daily oral care routines.\u003c\/p\u003e\n\u003cul data-start=\"697\" data-end=\"994\"\u003e\n\u003cli data-start=\"697\" data-end=\"794\"\u003e\n\u003cp data-start=\"699\" data-end=\"794\"\u003e\u003cstrong data-start=\"699\" data-end=\"724\"\u003eFull Spectrum Formula\u003c\/strong\u003e: Made only with full extract, natural terpenes, and plant material.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"795\" data-end=\"861\"\u003e\n\u003cp data-start=\"797\" data-end=\"861\"\u003e\u003cstrong data-start=\"797\" data-end=\"818\"\u003eBalance \u0026amp; Harmony\u003c\/strong\u003e: Pure CBG in a full extract formulation.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"936\" data-end=\"994\"\u003e\n\u003cp data-start=\"938\" data-end=\"994\"\u003e\u003cstrong data-start=\"938\" data-end=\"953\"\u003ePlant-Based\u003c\/strong\u003e: With carefully selected natural oils.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e🧪 \u003cstrong data-start=\"99\" data-end=\"113\"\u003eHow to Use\u003c\/strong\u003e\u003cbr data-start=\"113\" data-end=\"116\"\u003e• Shake well before use\u003cbr data-start=\"139\" data-end=\"142\"\u003e• Apply a small amount 2–3 times daily, preferably every day\u003cbr data-start=\"280\" data-end=\"283\"\u003e• Store in a cool, dark place at room temperature (15–25 °C)\u003c\/p\u003e\n\u003cp data-start=\"1342\" data-end=\"1460\"\u003e\u003cem data-end=\"241\" data-start=\"121\"\u003eWant to learn more about cannabigerol and its properties in oral care and wellness products? Check out this short blog.\u003c\/em\u003e\u003c\/p\u003e\n\u003ch1 data-start=\"0\" data-end=\"64\"\u003e🧬 Cannabigerol (CBG) and Scientifically Documented Properties\u003c\/h1\u003e\n\u003cp data-start=\"66\" data-end=\"605\"\u003eCannabigerol (CBG) is a natural phytocannabinoid derived from the Cannabis sativa plant. It is the precursor (“parent cannabinoid”) to compounds like CBD and THC, but CBG itself is non-psychoactive (non-intoxicating), making it safe for daily use (\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36397993\/#:~:text=Cannabigerol%20,CBG%20is%20metabolized\" rel=\"noopener\" alt=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36397993\/#:~:text=Cannabigerol%20,CBG%20is%20metabolized\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003epubmed.ncbi.nlm.nih.gov\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e\u003c\/span\u003e\u003c\/span\u003e). CBG interacts with the body’s endocannabinoid system (ECS), which \u003cstrong data-start=\"417\" data-end=\"430\"\u003eregulates\u003c\/strong\u003e many key physiological functions – including mood, pain perception, sleep, immune and inflammatory responses (\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/www.health.harvard.edu\/blog\/the-endocannabinoid-system-essential-and-mysterious-202108112569#:~:text=which%20is%20amazing%20when%20you,international%20research%20and%20drug%20development\" rel=\"noopener\" alt=\"https:\/\/www.health.harvard.edu\/blog\/the-endocannabinoid-system-essential-and-mysterious-202108112569#:~:text=which%20is%20amazing%20when%20you,international%20research%20and%20drug%20development\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003ehealth.harvard.edu\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e\u003c\/span\u003e\u003c\/span\u003e)– to help maintain balance.\u003c\/p\u003e\n\u003ch2 data-start=\"607\" data-end=\"664\"\u003e📌 Key Properties Identified in Scientific Literature:\u003c\/h2\u003e\n\u003cul data-start=\"666\" data-end=\"3870\"\u003e\n\u003cli data-start=\"666\" data-end=\"1209\"\u003e\n\u003cp data-start=\"668\" data-end=\"1209\"\u003e\u003cstrong data-start=\"668\" data-end=\"698\"\u003eAnxiety and stress relief:\u003c\/strong\u003e Preclinical research indicates CBG has \u003cstrong data-start=\"738\" data-end=\"752\"\u003eanxiolytic\u003c\/strong\u003e effects, potentially by interacting with serotonin (5-HT₁ₐ) and adrenergic receptors to reduce anxiety (\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/www.cannamd.com\/intro-to-cbg\/#:~:text=In%20a%20study%20conducted%20at,improve%20mood%20and%20mental%20performance\" rel=\"noopener\" alt=\"https:\/\/www.cannamd.com\/intro-to-cbg\/#:~:text=In%20a%20study%20conducted%20at,improve%20mood%20and%20mental%20performance\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003ecannamd.com\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e\u003c\/span\u003e\u003c\/span\u003e). In a recent \u003cstrong data-start=\"906\" data-end=\"921\"\u003ehuman trial\u003c\/strong\u003e, a single 20 mg dose of CBG significantly lowered measured anxiety and stress levels without any intoxicating effects (\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/www.nature.com\/articles\/s41598-024-66879-0?error=cookies_not_supported\u0026amp;code=3f60e2f2-3a27-49c7-bd19-525df9bd2e2d#:~:text=Social%20Stress%20Test%20,and%20anxiety%20in%20healthy%20adults\" rel=\"noopener\" alt=\"https:\/\/www.nature.com\/articles\/s41598-024-66879-0?error=cookies_not_supported\u0026amp;code=3f60e2f2-3a27-49c7-bd19-525df9bd2e2d#:~:text=Social%20Stress%20Test%20,and%20anxiety%20in%20healthy%20adults\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003enature.com\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e\u003c\/span\u003e\u003c\/span\u003e). Early evidence includes studies of CBG in models of social stress and surveys of users reporting reduced anxiety and PTSD symptoms.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"1211\" data-end=\"1720\"\u003e\n\u003cp data-start=\"1213\" data-end=\"1720\"\u003e\u003cstrong data-start=\"1213\" data-end=\"1231\"\u003eSleep support:\u003c\/strong\u003e While research on CBG and sleep is still emerging, it may improve sleep quality and duration, especially when sleep disturbances are related to anxiety or pain. In a 2022 survey of CBG users, 31% reported using CBG for insomnia, with the majority rating it more effective than conventional sleep medications (\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/www.nature.com\/articles\/s41598-024-66879-0?error=cookies_not_supported\u0026amp;code=3f60e2f2-3a27-49c7-bd19-525df9bd2e2d#:~:text=perceived%20therapeutic%20effects%20of%20CBG%2C,and%20the%20use%20of%20preparations\" rel=\"noopener\" alt=\"https:\/\/www.nature.com\/articles\/s41598-024-66879-0?error=cookies_not_supported\u0026amp;code=3f60e2f2-3a27-49c7-bd19-525df9bd2e2d#:~:text=perceived%20therapeutic%20effects%20of%20CBG%2C,and%20the%20use%20of%20preparations\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003enature.com\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e\u003c\/span\u003e\u003c\/span\u003e). Many users noted falling asleep faster and deeper sleep when using CBG, suggesting a potential role in addressing stress-related sleep issues.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"1722\" data-end=\"2489\"\u003e\n\u003cp data-start=\"1724\" data-end=\"2489\"\u003e\u003cstrong data-start=\"1724\" data-end=\"1771\"\u003eAnti-inflammatory and analgesic properties:\u003c\/strong\u003e CBG influences multiple targets (CB₁, CB₂ cannabinoid receptors as well as TRP channels and adrenergic receptors) involved in pain signaling and inflammation (\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC9587780\/#:~:text=properties%20of%20CBG%20are%20hypothesized,neuroinflammation%2C%20CBG%20showed%20neuroprotective%20effects\" rel=\"noopener\" alt=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC9587780\/#:~:text=properties%20of%20CBG%20are%20hypothesized,neuroinflammation%2C%20CBG%20showed%20neuroprotective%20effects\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003epmc.ncbi.nlm.nih.gov\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC9587780\/#:~:text=or%20formalin%20injection%20in%20both,37.%20These\" rel=\"noopener\" alt=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC9587780\/#:~:text=or%20formalin%20injection%20in%20both,37.%20These\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003epmc.ncbi.nlm.nih.gov\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e\u003c\/span\u003e\u003c\/span\u003e). Preclinical studies have shown \u003cstrong data-start=\"2036\" data-end=\"2049\"\u003eanalgesic\u003c\/strong\u003e effects of CBG in models of chronic and neuropathic pain, and \u003cstrong data-start=\"2112\" data-end=\"2133\"\u003eanti-inflammatory\u003c\/strong\u003e activity in conditions like inflammatory bowel disease (\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/www.nature.com\/articles\/s41598-024-66879-0?error=cookies_not_supported\u0026amp;code=3f60e2f2-3a27-49c7-bd19-525df9bd2e2d#:~:text=activity4%20,effects%20indictive%20of%20THC%2033%2C11\" rel=\"noopener\" alt=\"https:\/\/www.nature.com\/articles\/s41598-024-66879-0?error=cookies_not_supported\u0026amp;code=3f60e2f2-3a27-49c7-bd19-525df9bd2e2d#:~:text=activity4%20,effects%20indictive%20of%20THC%2033%2C11\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003enature.com\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e\u003c\/span\u003e\u003c\/span\u003e). For example, CBG reduced inflammatory markers and nitric oxide in a mouse colitis study, leading to less intestinal inflammation (\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23415610\/#:~:text=receptor%20antagonist,clinical%20experimentation%20in%20IBD%20patients\" rel=\"noopener\" alt=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23415610\/#:~:text=receptor%20antagonist,clinical%20experimentation%20in%20IBD%20patients\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003epubmed.ncbi.nlm.nih.gov\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e\u003c\/span\u003e\u003c\/span\u003e). These findings support CBG’s potential to help relieve persistent pain and reduce inflammation.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"2491\" data-end=\"3072\"\u003e\n\u003cp data-start=\"2493\" data-end=\"3072\"\u003e\u003cstrong data-start=\"2493\" data-end=\"2533\"\u003ePhysiological balance (homeostasis):\u003c\/strong\u003e By modulating the ECS, CBG may support general well-being and \u003cstrong data-start=\"2596\" data-end=\"2616\"\u003einternal balance\u003c\/strong\u003e. CBG is known to be a partial agonist at ECS receptors and even helps regulate endocannabinoid signaling (\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36397993\/#:~:text=characteristics%20and%20on%20its%20principal,stimulating%20effects\" rel=\"noopener\" alt=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36397993\/#:~:text=characteristics%20and%20on%20its%20principal,stimulating%20effects\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003epubmed.ncbi.nlm.nih.gov\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e\u003c\/span\u003e\u003c\/span\u003e). This means it can tone the activity of various neurotransmitters and immune mediators to maintain homeostasis. Many cannabinoids exhibit adaptogenic-like effects in the body, and CBG’s broad receptor interactions suggest it similarly contributes to equilibrium in bodily systems (mood, immunity, appetite, etc.).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"3074\" data-end=\"3870\"\u003e\n\u003cp data-start=\"3076\" data-end=\"3870\"\u003e\u003cstrong data-start=\"3076\" data-end=\"3121\"\u003eAntioxidant and immunomodulatory effects:\u003c\/strong\u003e Experimental data suggest CBG has notable \u003cstrong data-start=\"3164\" data-end=\"3179\"\u003eantioxidant\u003c\/strong\u003e capacity and can modulate immune responses. In cell studies, CBG significantly reduced reactive oxygen species (ROS) levels – performing better than vitamin C as an antioxidant – and inhibited the release of pro-inflammatory cytokines (like IL-1β, IL-6, IL-8, and TNF-α) under stress conditions (\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/www.researchgate.net\/publication\/357841510_In_Vitro_and_Clinical_Evaluation_of_Cannabigerol_CBG_Produced_via_Yeast_Biosynthesis_A_Cannabinoid_with_a_Broad_Range_of_Anti-Inflammatory_and_Skin_Health-Boosting_Properties#:~:text=in%20culture%20to%20pro,serum%20showed%20statistically%20significant%20improvement\" rel=\"noopener\" alt=\"https:\/\/www.researchgate.net\/publication\/357841510_In_Vitro_and_Clinical_Evaluation_of_Cannabigerol_CBG_Produced_via_Yeast_Biosynthesis_A_Cannabinoid_with_a_Broad_Range_of_Anti-Inflammatory_and_Skin_Health-Boosting_Properties#:~:text=in%20culture%20to%20pro,serum%20showed%20statistically%20significant%20improvement\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003eresearchgate.net\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e\u003c\/span\u003e\u003c\/span\u003e). These immunomodulatory effects include boosting anti-inflammatory interleukins while dampening excessive inflammatory signals (\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23415610\/#:~:text=receptor%20antagonist,clinical%20experimentation%20in%20IBD%20patients\" rel=\"noopener\" alt=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23415610\/#:~:text=receptor%20antagonist,clinical%20experimentation%20in%20IBD%20patients\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003epubmed.ncbi.nlm.nih.gov\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e\u003c\/span\u003e\u003c\/span\u003e). Such findings align with other research showing CBG’s neuroprotective and immune-calming effects, indicating it may help protect cells from oxidative stress and overactive immune reactions.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 data-start=\"3872\" data-end=\"3907\"\u003e🦷 CBG in Oral Care Applications\u003c\/h2\u003e\n\u003cp data-start=\"3909\" data-end=\"4108\"\u003eRecent \u003cstrong data-start=\"3916\" data-end=\"3928\"\u003ein vitro\u003c\/strong\u003e studies have started evaluating CBG for topical use in the oral cavity due to its antimicrobial, anti-inflammatory, and soothing properties (\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/www.frontiersin.org\/journals\/microbiology\/articles\/10.3389\/fmicb.2021.656471\/full#:~:text=Streptococcus%20mutans%20%28S,treated\" rel=\"noopener\" alt=\"https:\/\/www.frontiersin.org\/journals\/microbiology\/articles\/10.3389\/fmicb.2021.656471\/full#:~:text=Streptococcus%20mutans%20%28S,treated\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003efrontiersin.org\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e\u003c\/span\u003e\u003c\/span\u003e):\u003c\/p\u003e\n\u003cul data-start=\"4110\" data-end=\"6494\"\u003e\n\u003cli data-start=\"4110\" data-end=\"4738\"\u003e\n\u003cp data-start=\"4112\" data-end=\"4738\"\u003e\u003cstrong data-start=\"4112\" data-end=\"4137\"\u003eAntibacterial action:\u003c\/strong\u003e CBG shows antimicrobial activity against common oral pathogens, such as \u003cem data-start=\"4210\" data-end=\"4232\"\u003eStreptococcus mutans\u003c\/em\u003e (a primary bacterium involved in dental caries) (\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/www.frontiersin.org\/journals\/microbiology\/articles\/10.3389\/fmicb.2021.656471\/full#:~:text=Streptococcus%20mutans%20%28S,treated\" rel=\"noopener\" alt=\"https:\/\/www.frontiersin.org\/journals\/microbiology\/articles\/10.3389\/fmicb.2021.656471\/full#:~:text=Streptococcus%20mutans%20%28S,treated\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003efrontiersin.org\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e\u003c\/span\u003e\u003c\/span\u003e). Laboratory tests demonstrate that CBG can halt the growth of \u003cem data-start=\"4382\" data-end=\"4393\"\u003eS. mutans\u003c\/em\u003e and disrupt its bacterial membrane, indicating potential to combat dental plaque and cavities. This broad antibacterial effect likely extends to other oral bacteria that contribute to gum disease and bad breath (similar cannabinoids have shown effectiveness against \u003cem data-start=\"4660\" data-end=\"4686\"\u003ePorphyromonas gingivalis\u003c\/em\u003e and others) (\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/www.frontiersin.org\/journals\/microbiology\/articles\/10.3389\/fmicb.2021.656471\/full#:~:text=cannabinoids%20have%20been%20found%20to,CBG%20treatment%20leads%20to%20intracellular\" rel=\"noopener\" alt=\"https:\/\/www.frontiersin.org\/journals\/microbiology\/articles\/10.3389\/fmicb.2021.656471\/full#:~:text=cannabinoids%20have%20been%20found%20to,CBG%20treatment%20leads%20to%20intracellular\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003efrontiersin.org\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e\u003c\/span\u003e\u003c\/span\u003e).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"4740\" data-end=\"5309\"\u003e\n\u003cp data-start=\"4742\" data-end=\"5309\"\u003e\u003cstrong data-start=\"4742\" data-end=\"4792\"\u003eComparable to chlorhexidine, without staining:\u003c\/strong\u003e In preliminary comparisons, cannabinoids like CBG have demonstrated plaque-fighting effects \u003cstrong data-start=\"4885\" data-end=\"4911\"\u003ecomparable or superior\u003c\/strong\u003e to chlorhexidine (a standard medicated mouthwash), \u003cstrong data-start=\"4963\" data-end=\"4974\"\u003ewithout\u003c\/strong\u003e the drawbacks. Notably, long-term chlorhexidine use is known to cause tooth staining as a side effect, whereas CBG-based formulations would not cause such discoloration. This suggests CBG could offer a natural alternative for oral antisepsis that avoids the brownish staining and taste alteration associated with chlorhexidine rinses.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"5311\" data-end=\"5954\"\u003e\n\u003cp data-start=\"5313\" data-end=\"5954\"\u003e\u003cstrong data-start=\"5313\" data-end=\"5348\"\u003eWell tolerated by oral tissues:\u003c\/strong\u003e CBG is well tolerated by oral mucosal tissues, with no signs of irritation, burning sensation, or tissue damage observed in tests (\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/www.researchgate.net\/publication\/357841510_In_Vitro_and_Clinical_Evaluation_of_Cannabigerol_CBG_Produced_via_Yeast_Biosynthesis_A_Cannabinoid_with_a_Broad_Range_of_Anti-Inflammatory_and_Skin_Health-Boosting_Properties#:~:text=CBD.%20A%2020,be%20more%20effective%20than%20CBD\" rel=\"noopener\" alt=\"https:\/\/www.researchgate.net\/publication\/357841510_In_Vitro_and_Clinical_Evaluation_of_Cannabigerol_CBG_Produced_via_Yeast_Biosynthesis_A_Cannabinoid_with_a_Broad_Range_of_Anti-Inflammatory_and_Skin_Health-Boosting_Properties#:~:text=CBD.%20A%2020,be%20more%20effective%20than%20CBD\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003eresearchgate.net\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e\u003c\/span\u003e\u003c\/span\u003e). In fact, CBG’s \u003cstrong data-start=\"5534\" data-end=\"5546\"\u003esoothing\u003c\/strong\u003e and anti-inflammatory properties may help calm gum irritation. Studies on topical CBG (in skin applications) found it to be a safe, non-irritating ingredient (\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/www.researchgate.net\/publication\/357841510_In_Vitro_and_Clinical_Evaluation_of_Cannabigerol_CBG_Produced_via_Yeast_Biosynthesis_A_Cannabinoid_with_a_Broad_Range_of_Anti-Inflammatory_and_Skin_Health-Boosting_Properties#:~:text=above%20placebo%20for%20transepidermal%20water,be%20more%20effective%20than%20CBD\" rel=\"noopener\" alt=\"https:\/\/www.researchgate.net\/publication\/357841510_In_Vitro_and_Clinical_Evaluation_of_Cannabigerol_CBG_Produced_via_Yeast_Biosynthesis_A_Cannabinoid_with_a_Broad_Range_of_Anti-Inflammatory_and_Skin_Health-Boosting_Properties#:~:text=above%20placebo%20for%20transepidermal%20water,be%20more%20effective%20than%20CBD\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003eresearchgate.net\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e\u003c\/span\u003e\u003c\/span\u003e), and by extension, a CBG oral product is expected to be gentle on the gums and oral epithelium. Users of CBG oral oils have not reported issues like oral burning or mouth dryness beyond mild, transient effects.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"5956\" data-end=\"6494\"\u003e\n\u003cp data-start=\"5958\" data-end=\"6494\"\u003e\u003cstrong data-start=\"5958\" data-end=\"5984\"\u003eFormulation stability:\u003c\/strong\u003e CBG can be effectively stabilized in carrier oils (such as medium-chain triglyceride (MCT) coconut oil or olive oil) which also enhance its delivery in oral formulations. Formulating CBG in lipid-based carriers protects the cannabinoid from degradation and improves its absorption into oral tissues. This product utilizes such carrier oils to ensure that CBG remains potent and bioavailable when applied in the mouth. The oil base also helps the CBG distribute evenly across oral surfaces for maximum benefit.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-start=\"6496\" data-end=\"6760\"\u003e\u003cstrong data-start=\"6496\" data-end=\"6505\"\u003eNote:\u003c\/strong\u003e This product is registered in the European CPNP database with Notification Number: CPNP 4680816.\u003c\/p\u003e\n\u003cp data-start=\"6762\" data-end=\"7014\"\u003eThe information presented is based on published scientific literature regarding cannabigerol (CBG) as a compound and is not intended as a health claim for the final product. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/p\u003e\n\u003ch2 data-start=\"7016\" data-end=\"7032\"\u003e📚 References\u003c\/h2\u003e\n\u003col data-start=\"7034\" data-end=\"8351\" data-is-last-node=\"\" data-is-only-node=\"\"\u003e\n\u003cli data-start=\"7034\" data-end=\"7192\"\u003e\n\u003cp data-start=\"7037\" data-end=\"7192\"\u003eCalapai, F., et al. (2022). \u003cem data-start=\"7069\" data-end=\"7124\"\u003eEvidence-Based Complementary and Alternative Medicine\u003c\/em\u003e, 2022, Article ID 3336516. \u003ca href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2022\/3336516\" title=\"CBG RESEARCH\" rel=\"noopener\" target=\"_blank\"\u003e\u003cspan href=\"https:\/\/doi.org\/10.1155\/2022\/3336516\" data-start=\"7156\" data-end=\"7192\" rel=\"noopener noreferrer\"\u003ehttps:\/\/doi.org\/10.1155\/2022\/3336516\u003c\/span\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"7194\" data-end=\"7398\"\u003e\n\u003cp data-start=\"7197\" data-end=\"7398\"\u003eGrinspoon, P. (2021). \u003cem data-start=\"7219\" data-end=\"7246\"\u003eHarvard Health Publishing\u003c\/em\u003e – \u003cem data-start=\"7249\" data-end=\"7303\"\u003eThe endocannabinoid system: Essential and mysterious\u003c\/em\u003e. (Blog article) Harvard Health Blog. \u003cem data-start=\"7341\" data-end=\"7398\"\u003e(Note: ECS regulates multiple physiological functions.)\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"7400\" data-end=\"7514\"\u003e\n\u003cp data-start=\"7403\" data-end=\"7514\"\u003eCuttler, C., et al. (2024). \u003cem data-start=\"7435\" data-end=\"7455\"\u003eScientific Reports\u003c\/em\u003e, 14, 16163. \u003ca href=\"https:\/\/www.nature.com\/articles\/s41598-024-66879-0\" title=\"CBG CANNABIGEROL RESEARCH\" rel=\"noopener\" target=\"_blank\"\u003e\u003cspan href=\"https:\/\/doi.org\/10.1038\/s41598-024-66879-0\" data-start=\"7472\" data-end=\"7514\" rel=\"noopener noreferrer\"\u003ehttps:\/\/doi.org\/10.1038\/s41598-024-66879-0\u003c\/span\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"7516\" data-end=\"7645\"\u003e\n\u003cp data-start=\"7519\" data-end=\"7645\"\u003eRusso, E. B., et al. (2022). \u003cem data-start=\"7552\" data-end=\"7587\"\u003eCannabis and Cannabinoid Research\u003c\/em\u003e, 7(4), 706–716. \u003ca href=\"https:\/\/www.liebertpub.com\/doi\/10.1089\/can.2021.0058\" title=\"CANNABINOID RESEARCH\" rel=\"noopener\" target=\"_blank\"\u003e\u003cspan href=\"https:\/\/doi.org\/10.1089\/can.2021.0058\" data-start=\"7608\" data-end=\"7645\" rel=\"noopener noreferrer\"\u003ehttps:\/\/doi.org\/10.1089\/can.2021.0058\u003c\/span\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"7647\" data-end=\"7774\"\u003e\n\u003cp data-start=\"7650\" data-end=\"7774\"\u003eBorrelli, F., et al. (2013). \u003cem data-start=\"7683\" data-end=\"7709\"\u003eBiochemical Pharmacology\u003c\/em\u003e, 85(9), 1306–1316. \u003ca href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0006295213000543?via%3Dihub\" title=\"CANNABINOID RESEARCH\" rel=\"noopener\" target=\"_blank\"\u003e\u003cspan href=\"https:\/\/doi.org\/10.1016\/j.bcp.2013.01.017\" data-start=\"7733\" data-end=\"7774\" rel=\"noopener noreferrer\"\u003ehttps:\/\/doi.org\/10.1016\/j.bcp.2013.01.017\u003c\/span\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"7776\" data-end=\"7879\"\u003e\n\u003cp data-start=\"7779\" data-end=\"7879\"\u003ePerez, E., et al. (2022). \u003cem data-start=\"7809\" data-end=\"7820\"\u003eMolecules\u003c\/em\u003e, 27(2), 491. \u003ca href=\"https:\/\/www.mdpi.com\/1420-3049\/27\/2\/491\" title=\"CANNABINOID REASEARCH ABOUT CBG (CANNABIGEROL)\" rel=\"noopener\" target=\"_blank\"\u003e\u003cspan href=\"https:\/\/doi.org\/10.3390\/molecules27020491\" data-start=\"7838\" data-end=\"7879\" rel=\"noopener noreferrer\"\u003ehttps:\/\/doi.org\/10.3390\/molecules27020491\u003c\/span\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"7881\" data-end=\"8000\"\u003e\n\u003cp data-start=\"7884\" data-end=\"8000\"\u003eAqawi, M., et al. (2021). \u003cem data-start=\"7914\" data-end=\"7941\"\u003eFrontiers in Microbiology\u003c\/em\u003e, 12, 656471. \u003ca href=\"https:\/\/www.frontiersin.org\/journals\/microbiology\/articles\/10.3389\/fmicb.2021.656471\/full\" title=\"CBG\" rel=\"noopener\" target=\"_blank\"\u003e\u003cspan href=\"https:\/\/doi.org\/10.3389\/fmicb.2021.656471\" data-start=\"7959\" data-end=\"8000\" rel=\"noopener noreferrer\"\u003ehttps:\/\/doi.org\/10.3389\/fmicb.2021.656471\u003c\/span\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"8002\" data-end=\"8143\"\u003e\n\u003cp data-start=\"8005\" data-end=\"8143\"\u003ePoppolo-Deus, F., \u0026amp; Ouanounou, A. (2022). \u003cem data-start=\"8047\" data-end=\"8077\"\u003eInternational Dental Journal\u003c\/em\u003e, 72(3), 269–277. \u003ca href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0020653922000259?via%3Dihub\" title=\"CBG\" rel=\"noopener\" target=\"_blank\"\u003e\u003cspan href=\"https:\/\/doi.org\/10.1016\/j.identj.2022.01.005\" data-start=\"8099\" data-end=\"8143\" rel=\"noopener noreferrer\"\u003ehttps:\/\/doi.org\/10.1016\/j.identj.2022.01.005\u003c\/span\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"8145\" data-end=\"8242\"\u003e\n\u003cp data-start=\"8148\" data-end=\"8242\"\u003eRegulation (EU) No 1307\/2013 and Directive 2002\/46\/EC – EU compliance on hemp and novel foods.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"8244\" data-end=\"8351\" data-is-last-node=\"\"\u003e\n\u003cp data-start=\"8248\" data-end=\"8351\" data-is-last-node=\"\"\u003e\u003cem data-start=\"8248\" data-end=\"8351\" data-is-last-node=\"\"\u003eCPNP Notification Number: 4680815 (Product registration in EU Cosmetic Products Notification Portal).\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"CRETAN GAIA PRODUCTS","offers":[{"title":"Default Title","offer_id":53231330918728,"sku":"CG2905","price":19.02,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0968\/7603\/6424\/files\/18a60006-ee06-48fa-a96c-8bdfb0d0d7ed.jpg?v=1780577081"},{"product_id":"natura-inside-hemp-wax-cream-300mg-broad-spectrum-cbd-20mg-piperine-40ml","title":"Natura Inside Hemp Wax Cream – 300mg Broad Spectrum CBD, 20mg Piperine, 40ml","description":"\u003cp data-start=\"182\" data-end=\"245\"\u003e\u003cstrong data-start=\"182\" data-end=\"243\"\u003eHEMP WAX CREAM – Natural Care for Healthy and Smooth Skin\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-start=\"247\" data-end=\"515\"\u003eThe Hemp Wax Cream is designed to provide nourishing care and long-lasting hydration. Enriched with CBD, olive oil, beeswax, and piperine, it helps maintain soft, smooth, and well-cared-for skin. Suitable for all skin types, it can be applied even on delicate areas.\u003c\/p\u003e\n\u003cp data-start=\"517\" data-end=\"536\"\u003e\u003cstrong data-start=\"517\" data-end=\"534\"\u003eKey Features:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul data-start=\"537\" data-end=\"935\"\u003e\n\u003cli data-start=\"537\" data-end=\"618\"\u003e\n\u003cp data-start=\"539\" data-end=\"618\"\u003e\u003cstrong data-start=\"539\" data-end=\"558\"\u003eDeep Hydration:\u003c\/strong\u003e Olive oil and beeswax contribute to soft and supple skin.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"619\" data-end=\"693\"\u003e\n\u003cp data-start=\"621\" data-end=\"693\"\u003e\u003cstrong data-start=\"621\" data-end=\"638\"\u003eSkin Comfort:\u003c\/strong\u003e With CBD extract for a soothing skincare experience.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"694\" data-end=\"763\"\u003e\n\u003cp data-start=\"696\" data-end=\"763\"\u003e\u003cstrong data-start=\"696\" data-end=\"712\"\u003eGentle Care:\u003c\/strong\u003e Suitable for use on sensitive areas of the skin.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"764\" data-end=\"843\"\u003e\n\u003cp data-start=\"766\" data-end=\"843\"\u003e\u003cstrong data-start=\"766\" data-end=\"787\"\u003eEnhanced Formula:\u003c\/strong\u003e Piperine supports the synergy of natural ingredients.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"844\" data-end=\"935\"\u003e\n\u003cp data-start=\"846\" data-end=\"935\"\u003e\u003cstrong data-start=\"846\" data-end=\"870\"\u003eNatural Composition:\u003c\/strong\u003e Made without artificial additives, offering gentle daily care.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-start=\"937\" data-end=\"962\"\u003e\u003cstrong data-start=\"937\" data-end=\"960\"\u003eDirections for Use:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul data-start=\"963\" data-end=\"1166\"\u003e\n\u003cli data-start=\"963\" data-end=\"1047\"\u003e\n\u003cp data-start=\"965\" data-end=\"1047\"\u003eApply a small amount to clean, dry skin and massage gently until fully absorbed.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"1048\" data-end=\"1108\"\u003e\n\u003cp data-start=\"1050\" data-end=\"1108\"\u003eIdeal for daily hydration or targeted skincare routines.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"1109\" data-end=\"1166\"\u003e\n\u003cp data-start=\"1111\" data-end=\"1166\"\u003eUse as often as needed for smooth and refreshed skin.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-start=\"1168\" data-end=\"1307\"\u003e\u003cstrong data-start=\"1168\" data-end=\"1187\"\u003eImportant Note:\u003c\/strong\u003e\u003cbr data-start=\"1187\" data-end=\"1190\"\u003eFor external use only. Avoid direct contact with the eyes. Not intended to diagnose, treat, or prevent any disease.\u003c\/p\u003e","brand":"Natura Inside","offers":[{"title":"Default Title","offer_id":53231331017032,"sku":"LW2903broad","price":7.77,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0968\/7603\/6424\/files\/relief.jpg?v=1780577082"},{"product_id":"natura-inside-full-spectrum-cannabis-oil-30-cbd-with-piperine-ydor-series-10ml","title":"Natura Inside Full Spectrum Cannabis Oil – 30% CBD with Piperine, Ydor Series, 10ml","description":"\u003ch3\u003e\u003cstrong\u003eCBD Oil 30% (10ml)\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eThis high-concentration oil contains \u003cstrong\u003e30% CBD (3000 mg per 10 ml)\u003c\/strong\u003e, derived from \u003cem\u003eCannabis sativa L.\u003c\/em\u003e, and is formulated with a \u003cstrong\u003efull spectrum of natural cannabinoids\u003c\/strong\u003e, terpenes, and other plant compounds. It offers a \u003cstrong\u003eclean botanical profile\u003c\/strong\u003e, enriched with \u003cstrong\u003epiperine\u003c\/strong\u003e for enhanced composition.\u003c\/p\u003e\n\u003chr\u003e\n\u003cp\u003e🌿 \u003cstrong\u003eKey Features\u003c\/strong\u003e\u003cbr\u003e• 30% CBD – 3000 mg per 10 ml\u003cbr\u003e• Full-spectrum extract from \u003cem\u003eCannabis sativa L.\u003c\/em\u003e\u003cbr\u003e• Contains piperine (black pepper extract)\u003cbr\u003e• Natural carrier oils: MCT (C8\/C10 triglycerides) derived from coconut oil, Greek olive oil, and cold-pressed sunflower oil\u003cbr\u003e• Neutral, earthy taste from plant terpenes\u003cbr\u003e• No artificial ingredients, preservatives, or solvents\u003c\/p\u003e\n\u003chr\u003e\n\u003cp\u003e🧪 \u003cstrong data-start=\"99\" data-end=\"113\"\u003eHow to Use\u003c\/strong\u003e\u003cbr data-start=\"113\" data-end=\"116\"\u003e• Shake well before use\u003cbr data-start=\"139\" data-end=\"142\"\u003e• Apply a small amount 2–3 times daily, preferably every day\u003cbr data-start=\"280\" data-end=\"283\"\u003e• Store in a cool, dark place at room temperature (15–25 °C)\u003c\/p\u003e\n\u003cp data-end=\"243\" data-start=\"98\"\u003e\u003cem data-end=\"241\" data-start=\"121\"\u003eWant to learn more about cannabidiol and its properties in oral care and wellness products? Check out this short blog.\u003c\/em\u003e\u003c\/p\u003e\n\u003chr\u003e\n\u003ch3\u003e🧬 \u003cstrong\u003eCannabidiol (CBD) and Scientifically Documented Properties\u003c\/strong\u003e\n\u003c\/h3\u003e\n\u003cp\u003eCannabidiol (CBD) is a natural phytocannabinoid derived from the \u003cem\u003eCannabis sativa\u003c\/em\u003e plant. Unlike tetrahydrocannabinol (THC), CBD is \u003cstrong\u003enon-psychoactive\u003c\/strong\u003e, making it safe for daily use¹. It interacts with the \u003cstrong\u003eendocannabinoid system (ECS)\u003c\/strong\u003e, which regulates key physiological functions such as anxiety, pain, sleep, and immune balance².\u003c\/p\u003e\n\u003chr\u003e\n\u003cp\u003e📌 \u003cstrong\u003eKey Properties Identified in Scientific Literature:\u003c\/strong\u003e\u003cbr\u003e• \u003cstrong\u003eAnxiety and stress relief\u003c\/strong\u003e: CBD appears to interact with serotonin receptors, contributing to anxiolytic effects³. It has been studied in cases of social anxiety, generalized anxiety disorder, and PTSD.\u003cbr\u003e• \u003cstrong\u003eSleep support\u003c\/strong\u003e: Research shows that CBD may improve sleep quality and duration, particularly when sleep disturbances are related to anxiety⁴.\u003cbr\u003e• \u003cstrong\u003eAnti-inflammatory and analgesic properties\u003c\/strong\u003e: CBD influences CB1, CB2, and TRPV1 receptors, supporting relief from chronic or neuropathic pain and reducing inflammation⁵.\u003cbr\u003e• \u003cstrong\u003ePhysiological balance (homeostasis)\u003c\/strong\u003e: By modulating the ECS, CBD may help support general wellbeing and internal balance⁶.\u003cbr\u003e• \u003cstrong\u003eAntioxidant and immunomodulatory effects\u003c\/strong\u003e: Experimental data suggest CBD may reduce pro-inflammatory cytokines and support immune response⁷.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch3\u003e🦷 \u003cstrong\u003eCBD in Oral Care Applications\u003c\/strong\u003e\n\u003c\/h3\u003e\n\u003cp\u003eRecent \u003cstrong\u003ein vitro\u003c\/strong\u003e studies have evaluated CBD for topical use in the oral cavity due to its \u003cstrong\u003eantimicrobial, anti-inflammatory, and soothing properties⁸\u003c\/strong\u003e:\u003c\/p\u003e\n\u003cp\u003e• Shows antimicrobial activity against common oral pathogens such as \u003cem\u003eStreptococcus mutans\u003c\/em\u003e and \u003cem\u003ePorphyromonas gingivalis⁸\u003c\/em\u003e\u003cbr\u003e• Demonstrates effects comparable or superior to chlorhexidine, without side effects like staining⁹\u003cbr\u003e• Well tolerated by oral tissues — no irritation, burning, or discoloration⁸\u003cbr\u003e• Effectively stabilized in carrier oils such as MCT and olive oil, which enhance delivery in oral formulations⁸\u003c\/p\u003e\n\u003chr\u003e\n\u003cp\u003e\u003cstrong\u003eNote:\u003c\/strong\u003e This product is registered in the European CPNP database with \u003cstrong\u003eNotification Number: CPNP 4470920\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cp\u003eThe information presented is based on published scientific literature regarding \u003cstrong\u003ecannabidiol (CBD)\u003c\/strong\u003e as a compound and \u003cstrong\u003edoes not constitute a health claim\u003c\/strong\u003e for the final product. This product is \u003cstrong\u003enot intended to diagnose, treat, cure, or prevent any disease\u003c\/strong\u003e.\u003c\/p\u003e\n\u003chr\u003e\n\u003cp\u003e📚 \u003cstrong\u003eReferences\u003c\/strong\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cp\u003eWorld Health Organization. (2018). \u003cem\u003eCannabidiol (CBD) Critical Review Report\u003c\/em\u003e.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eLowe, H. I. C., Toyang, N. J., \u0026amp; McLaughlin, W. (2021). \u003cem\u003eMedicines\u003c\/em\u003e, 8(6), 44. \u003ca href=\"https:\/\/doi.org\/10.3390\/molecules26237216\"\u003ehttps:\/\/doi.org\/10.3390\/medicines8060044\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eBlessing, E. M., et al. (2015). \u003cem\u003eNeurotherapeutics\u003c\/em\u003e, 12(4), 825–836. \u003ca href=\"https:\/\/doi.org\/10.1007\/s13311-015-0387-1\"\u003ehttps:\/\/doi.org\/10.1007\/s13311-015-0387-1\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eShannon, S., et al. (2019). \u003cem\u003eThe Permanente Journal\u003c\/em\u003e, 23. \u003ca href=\"https:\/\/doi.org\/10.7812\/TPP\/18-041\"\u003ehttps:\/\/doi.org\/10.7812\/TPP\/18-041\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eWhiting, P. F., et al. (2015). \u003cem\u003eJAMA\u003c\/em\u003e, 313(24), 2456–2473. \u003ca href=\"https:\/\/doi.org\/10.1001\/jama.2015.6358\"\u003ehttps:\/\/doi.org\/10.1001\/jama.2015.6358\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eNichols, J. M., \u0026amp; Kaplan, B. L. (2020). \u003cem\u003eCannabis and Cannabinoid Research\u003c\/em\u003e, 5(1), 12–31. \u003ca href=\"https:\/\/doi.org\/10.1089\/can.2018.0073\"\u003ehttps:\/\/doi.org\/10.1089\/can.2018.0073\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eKozela, E., et al. (2011). \u003cem\u003eJournal of Neuroimmune Pharmacology\u003c\/em\u003e, 6(3), 529–540. \u003ca href=\"https:\/\/doi.org\/10.1111\/j.1476-5381.2011.01379.x\" aria-label=\"Digital Object Identifier for Cannabidiol inhibits pathogenic T cells, decreases spinal microglial activation and ameliorates multiple sclerosis-like disease in C57BL\/6 mice link\" class=\"epub-doi\"\u003ehttps:\/\/doi.org\/10.1111\/j.1476-5381.2011.01379.x\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eStahl, V., \u0026amp; Vasudevan, K. (2020). \u003cem\u003eCureus\u003c\/em\u003e, 12(1), e6809. \u003ca href=\"https:\/\/doi.org\/10.7759\/cureus.6809\"\u003ehttps:\/\/doi.org\/10.7759\/cureus.6809\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eIffland, K., \u0026amp; Grotenhermen, F. (2017). \u003cem\u003eCannabis and Cannabinoid Research\u003c\/em\u003e, 2(1), 139–154. \u003ca href=\"https:\/\/doi.org\/10.1089\/can.2016.0034\"\u003ehttps:\/\/doi.org\/10.1089\/can.2016.0034\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eRegulation (EU) No 1307\/2013 and Directive 2002\/46\/EC – \u003cstrong\u003eEU compliance on hemp and novel foods\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"Natura Inside","offers":[{"title":"Default Title","offer_id":53231330984264,"sku":"LA2930","price":28.53,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0968\/7603\/6424\/files\/30.webp?v=1780577080"},{"product_id":"cretan-gaia-full-extract-magic-pair-cannabis-oil-5-cbd-5-cbg-10ml","title":"Cretan Gaia Full Extract Magic Pair Cannabis Oil – 5% CBD \u0026 5% CBG, 10ml","description":"\u003cp data-end=\"254\" data-start=\"187\"\u003e\u003cstrong data-end=\"252\" data-start=\"187\"\u003eCRETAN GAIA Full Extract Magic Pair Oil 5% CBD \u0026amp; 5% CBG, 10ml\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-end=\"510\" data-start=\"256\"\u003eThe \u003cstrong data-end=\"290\" data-start=\"260\"\u003eCRETAN GAIA Magic Pair Oil\u003c\/strong\u003e combines CBD and CBG in equal concentration for a balanced full-extract formula. Carefully crafted from natural hemp extract, it provides a natural way to integrate phytocannabinoids into your daily oral care routine.\u003cstrong data-end=\"535\" data-start=\"514\"\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e🧪 \u003cstrong data-start=\"99\" data-end=\"113\"\u003eHow to Use\u003c\/strong\u003e\u003cbr data-start=\"113\" data-end=\"116\"\u003e• Shake well before use\u003cbr data-start=\"139\" data-end=\"142\"\u003e• Apply a small amount 2–3 times daily, preferably every day\u003cbr data-start=\"280\" data-end=\"283\"\u003e• Store in a cool, dark place at room temperature (15–25 °C)\u003c\/p\u003e\n\u003cp data-end=\"731\" data-start=\"715\"\u003e\u003cem data-end=\"241\" data-start=\"121\"\u003eWant to learn more about cannabidiol+cannabigerol combination and their properties in oral care and wellness products? Check out this short blog.\u003c\/em\u003e\u003c\/p\u003e\n\u003ch1 data-start=\"0\" data-end=\"103\"\u003e🧬 Cannabidiol (CBD) \u0026amp; Cannabigerol (CBG): Combined Benefits and Scientifically Documented Properties\u003c\/h1\u003e\n\u003cp data-start=\"105\" data-end=\"695\"\u003e\u003cstrong data-start=\"105\" data-end=\"126\"\u003eCannabidiol (CBD)\u003c\/strong\u003e and \u003cstrong data-start=\"131\" data-end=\"153\"\u003eCannabigerol (CBG)\u003c\/strong\u003e are two natural phytocannabinoids derived from the \u003cem data-start=\"205\" data-end=\"222\"\u003eCannabis sativa\u003c\/em\u003e plant. CBD is one of the most prevalent cannabinoids found in hemp, while CBG is a minor cannabinoid often called the “parent” molecule (CBG-A is the precursor from which other cannabinoids like CBD and THC form). Importantly, \u003cstrong data-start=\"450\" data-end=\"491\"\u003eboth CBD and CBG are non-psychoactive\u003c\/strong\u003e, meaning they do \u003cstrong data-start=\"509\" data-end=\"516\"\u003enot\u003c\/strong\u003e produce a “high” or intoxication. They are considered safe for daily use, with CBD even recognized by the WHO for having no abuse potential\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e (\u003ca href=\"https:\/\/www.health.harvard.edu\/blog\/cannabidiol-cbd-what-we-know-and-what-we-dont-201808242496#:~:text=According%20to%20a%20report%20from,daily%20functioning%20or%20workplace%20performance\" rel=\"noopener\" alt=\"https:\/\/www.health.harvard.edu\/blog\/cannabidiol-cbd-what-we-know-and-what-we-dont-201808242496#:~:text=According%20to%20a%20report%20from,daily%20functioning%20or%20workplace%20performance\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003ehealth.harvard.edu\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e\u003c\/span\u003e\u003c\/span\u003e).\u003c\/p\u003e\n\u003cp data-start=\"697\" data-end=\"1562\"\u003eBoth compounds interact with the body’s \u003cstrong data-start=\"737\" data-end=\"769\"\u003eendocannabinoid system (ECS)\u003c\/strong\u003e – a critical regulatory network that helps maintain balance (homeostasis). The ECS \u003cstrong data-start=\"853\" data-end=\"899\"\u003eregulates many key physiological functions\u003c\/strong\u003e including mood, stress response, pain sensation, immune activity, inflammation, sleep, and appetite (\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/www.health.harvard.edu\/blog\/the-endocannabinoid-system-essential-and-mysterious-202108112569#:~:text=Fewer%20have%20heard%20of%20the,international%20research%20and%20drug%20development\" rel=\"noopener\" alt=\"https:\/\/www.health.harvard.edu\/blog\/the-endocannabinoid-system-essential-and-mysterious-202108112569#:~:text=Fewer%20have%20heard%20of%20the,international%20research%20and%20drug%20development\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003ehealth.harvard.edu\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e\u003c\/span\u003e\u003c\/span\u003e). By modulating this system’s receptors and signaling pathways, CBD and CBG can influence these functions to support internal balance. Notably, CBG is a partial agonist at cannabinoid receptors and can even help regulate our own endocannabinoid levels (\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/www.researchgate.net\/publication\/235647806_Beneficial_effect_of_the_non-psychotropic_plant_cannabinoid_cannabigerol_on_experimental_inflammatory_bowel_disease#:~:text=Show%20abstract\" rel=\"noopener\" alt=\"https:\/\/www.researchgate.net\/publication\/235647806_Beneficial_effect_of_the_non-psychotropic_plant_cannabinoid_cannabigerol_on_experimental_inflammatory_bowel_disease#:~:text=Show%20abstract\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003eresearchgate.net\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e)\u003c\/span\u003e\u003c\/span\u003e, while CBD interacts indirectly (for example, by influencing serotonin and other receptors) to tone ECS activity (\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/www.researchgate.net\/publication\/235647806_Beneficial_effect_of_the_non-psychotropic_plant_cannabinoid_cannabigerol_on_experimental_inflammatory_bowel_disease#:~:text=termed%20the%20endocannabinoidome%20,\" rel=\"noopener\" alt=\"https:\/\/www.researchgate.net\/publication\/235647806_Beneficial_effect_of_the_non-psychotropic_plant_cannabinoid_cannabigerol_on_experimental_inflammatory_bowel_disease#:~:text=termed%20the%20endocannabinoidome%20,\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003eresearchgate.net\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e\u003c\/span\u003e\u003c\/span\u003e). This broad action on multiple targets underlies many of their health-related benefits.\u003c\/p\u003e\n\u003cp data-start=\"1564\" data-end=\"1622\"\u003e📌 \u003cstrong data-start=\"1567\" data-end=\"1622\"\u003eKey Properties Identified in Scientific Literature:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-start=\"1624\" data-end=\"2936\"\u003e\u003cstrong data-start=\"1624\" data-end=\"1654\"\u003eAnxiety and Stress Relief:\u003c\/strong\u003e Extensive research suggests both CBD and CBG have \u003cstrong data-start=\"1705\" data-end=\"1738\"\u003eanxiolytic (anxiety-reducing)\u003c\/strong\u003e effects. Preclinical studies show that each can reduce anxiety behaviors, likely by interacting with serotonin 5-HT₁ₐ receptors and other neuroreceptors involved in mood regulation (\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/nanobella.com\/blogs\/blog\/cbg-for-stress-relief?srsltid=AfmBOoocqCIhDUmaP2R4h43UKEB4R6RL_uqrMOt4T86f2P4jXFoZgaEl#:~:text=While%20both%20cannabinoids%2C%20CBG%20and,their%20mechanisms%20of%20action%20differ\" rel=\"noopener\" alt=\"https:\/\/nanobella.com\/blogs\/blog\/cbg-for-stress-relief?srsltid=AfmBOoocqCIhDUmaP2R4h43UKEB4R6RL_uqrMOt4T86f2P4jXFoZgaEl#:~:text=While%20both%20cannabinoids%2C%20CBG%20and,their%20mechanisms%20of%20action%20differ\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003enanobella.com\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e)\u003c\/span\u003e\u003c\/span\u003e. Human trials have also reported positive results. For example, a recent double-blind study found that a single 20 mg dose of CBG significantly \u003cstrong data-start=\"2101\" data-end=\"2149\"\u003elowered subjective anxiety and stress levels\u003c\/strong\u003e in healthy adults, with \u003cstrong data-start=\"2174\" data-end=\"2214\"\u003eno intoxicating or impairing effects\u003c\/strong\u003e observed (\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/www.nature.com\/articles\/s41598-024-66879-0?error=cookies_not_supported\u0026amp;code=4d646c30-8b97-424a-973b-c082034b9836#:~:text=In%20conclusion%2C%20results%20of%20this,of%20patients%20with%20anxiety%20disorders\" rel=\"noopener\" alt=\"https:\/\/www.nature.com\/articles\/s41598-024-66879-0?error=cookies_not_supported\u0026amp;code=4d646c30-8b97-424a-973b-c082034b9836#:~:text=In%20conclusion%2C%20results%20of%20this,of%20patients%20with%20anxiety%20disorders\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003enature.com\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e\u003c\/span\u003e\u003c\/span\u003e). CBD’s calming effects are likewise documented – acute CBD administration has reduced anxiety during simulated public speaking tests and in people with social anxiety disorder (\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/www.nature.com\/articles\/s43856-022-00202-8?error=cookies_not_supported\u0026amp;code=7e87341e-b2a8-499b-bea9-f9e5dae62f49#:~:text=have%20demonstrated%20anxiolytic%20effects%20of,with%20diverse%20cannabinoid%20profiles%20may\" rel=\"noopener\" alt=\"https:\/\/www.nature.com\/articles\/s43856-022-00202-8?error=cookies_not_supported\u0026amp;code=7e87341e-b2a8-499b-bea9-f9e5dae62f49#:~:text=have%20demonstrated%20anxiolytic%20effects%20of,with%20diverse%20cannabinoid%20profiles%20may\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003enature.com\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/www.nature.com\/articles\/s43856-022-00202-8?error=cookies_not_supported\u0026amp;code=7e87341e-b2a8-499b-bea9-f9e5dae62f49#:~:text=investigations%20all%20used%20study%20products,terpenoids%2C%20flavonoids%29%2038%2C15\" rel=\"noopener\" alt=\"https:\/\/www.nature.com\/articles\/s43856-022-00202-8?error=cookies_not_supported\u0026amp;code=7e87341e-b2a8-499b-bea9-f9e5dae62f49#:~:text=investigations%20all%20used%20study%20products,terpenoids%2C%20flavonoids%29%2038%2C15\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003enature.com\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e\u003c\/span\u003e\u003c\/span\u003e). Many users report that using \u003cstrong data-start=\"2541\" data-end=\"2565\"\u003eCBD and CBG together\u003c\/strong\u003e further enhances their sense of calm and resilience to stress. Early evidence supports this synergy: combining cannabinoids can engage multiple pathways to produce a greater anxiolytic effect (the “entourage effect”) (\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/www.nature.com\/articles\/s43856-022-00202-8?error=cookies_not_supported\u0026amp;code=7e87341e-b2a8-499b-bea9-f9e5dae62f49#:~:text=investigations%20all%20used%20study%20products,terpenoids%2C%20flavonoids%29%2038%2C15\" rel=\"noopener\" alt=\"https:\/\/www.nature.com\/articles\/s43856-022-00202-8?error=cookies_not_supported\u0026amp;code=7e87341e-b2a8-499b-bea9-f9e5dae62f49#:~:text=investigations%20all%20used%20study%20products,terpenoids%2C%20flavonoids%29%2038%2C15\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003enature.com\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e\u003c\/span\u003e\u003c\/span\u003e). In short, CBD and CBG may help take the edge off stress and promote a more balanced, relaxed mood without sedation.\u003c\/p\u003e\n\u003cp data-start=\"2938\" data-end=\"4192\"\u003e\u003cstrong data-start=\"2938\" data-end=\"2956\"\u003eSleep Support:\u003c\/strong\u003e While research is ongoing, both CBD and CBG show promise in supporting better sleep—especially when insomnia is related to anxiety or pain. By easing stress and discomfort, these cannabinoids can indirectly improve sleep quality. In a 2022 survey of CBG-predominant product users, \u003cstrong data-start=\"3238\" data-end=\"3277\"\u003e31% reported using CBG for insomnia\u003c\/strong\u003e, and the majority rated it \u003cstrong data-start=\"3305\" data-end=\"3359\"\u003emore effective than conventional sleep medications (\u003c\/strong\u003e\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/nanobella.com\/blogs\/blog\/cbg-for-stress-relief?srsltid=AfmBOoocqCIhDUmaP2R4h43UKEB4R6RL_uqrMOt4T86f2P4jXFoZgaEl#:~:text=,of%20the%20sample\" rel=\"noopener\" alt=\"https:\/\/nanobella.com\/blogs\/blog\/cbg-for-stress-relief?srsltid=AfmBOoocqCIhDUmaP2R4h43UKEB4R6RL_uqrMOt4T86f2P4jXFoZgaEl#:~:text=,of%20the%20sample\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003enanobella.com\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/nanobella.com\/blogs\/blog\/cbg-for-stress-relief?srsltid=AfmBOoocqCIhDUmaP2R4h43UKEB4R6RL_uqrMOt4T86f2P4jXFoZgaEl#:~:text=\" rel=\"noopener\" alt=\"https:\/\/nanobella.com\/blogs\/blog\/cbg-for-stress-relief?srsltid=AfmBOoocqCIhDUmaP2R4h43UKEB4R6RL_uqrMOt4T86f2P4jXFoZgaEl#:~:text=\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003enanobella.com\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e\u003c\/span\u003e\u003c\/span\u003e). Users frequently noted falling asleep faster and experiencing deeper, more restful sleep with CBG use. Similarly, CBD has been reported to help with sleep initiation and duration; studies suggest CBD may aid in both \u003cstrong data-start=\"3653\" data-end=\"3690\"\u003efalling asleep and staying asleep\u003c\/strong\u003e, in part by alleviating chronic pain and anxiety that interfere with sleep (\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/www.health.harvard.edu\/blog\/cannabidiol-cbd-what-we-know-and-what-we-dont-201808242496#:~:text=,research%20identifies%20how%20CBD%20may\" rel=\"noopener\" alt=\"https:\/\/www.health.harvard.edu\/blog\/cannabidiol-cbd-what-we-know-and-what-we-dont-201808242496#:~:text=,research%20identifies%20how%20CBD%20may\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003ehealth.harvard.edu\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e\u003c\/span\u003e\u003c\/span\u003e). Many individuals using \u003cstrong data-start=\"3829\" data-end=\"3865\"\u003ecombination CBD+CBG formulations\u003c\/strong\u003e before bed report an easier time unwinding and improved sleep continuity. Though formal clinical trials on combined use for insomnia are limited, the anecdotal and preliminary evidence indicates that these cannabinoids could play a useful role in managing stress-related sleep disturbances and improving overall sleep quality.\u003c\/p\u003e\n\u003cp data-start=\"4194\" data-end=\"6086\"\u003e\u003cstrong data-start=\"4194\" data-end=\"4258\"\u003eAnti-inflammatory and Analgesic (Pain-Relieving) Properties:\u003c\/strong\u003e CBD and CBG are both noted for their \u003cstrong data-start=\"4296\" data-end=\"4339\"\u003eanti-inflammatory and analgesic effects\u003c\/strong\u003e, acting through multiple pathways involved in pain signaling. CBD has been shown to reduce chronic pain and inflammation in a variety of models – for instance, research indicates CBD can lessen arthritis pain and inhibit inflammatory and neuropathic pain pathways (\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/www.health.harvard.edu\/blog\/cannabidiol-cbd-what-we-know-and-what-we-dont-201808242496#:~:text=,for%20tobacco%20and%20heroin%20under\" rel=\"noopener\" alt=\"https:\/\/www.health.harvard.edu\/blog\/cannabidiol-cbd-what-we-know-and-what-we-dont-201808242496#:~:text=,for%20tobacco%20and%20heroin%20under\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003ehealth.harvard.edu\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e\u003c\/span\u003e\u003c\/span\u003e). CBG likewise influences pain perception by binding to CB₁ and CB₂ cannabinoid receptors and other targets (like TRP ion channels and α\u0026lt;sub\u0026gt;2\u0026lt;\/sub\u0026gt;-adrenergic receptors) that modulate pain and inflammation (\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/www.researchgate.net\/publication\/235647806_Beneficial_effect_of_the_non-psychotropic_plant_cannabinoid_cannabigerol_on_experimental_inflammatory_bowel_disease#:~:text=termed%20the%20endocannabinoidome%20,\" rel=\"noopener\" alt=\"https:\/\/www.researchgate.net\/publication\/235647806_Beneficial_effect_of_the_non-psychotropic_plant_cannabinoid_cannabigerol_on_experimental_inflammatory_bowel_disease#:~:text=termed%20the%20endocannabinoidome%20,\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003eresearchgate.net\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e)\u003c\/span\u003e\u003c\/span\u003e. Preclinical studies on CBG have demonstrated significant pain-relieving activity: for example, in a rodent model of inflammatory bowel disease, CBG treatment led to reduced inflammatory markers (like nitric oxide and cytokines) and less colonic tissue damage (\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/www.researchgate.net\/publication\/235647806_Beneficial_effect_of_the_non-psychotropic_plant_cannabinoid_cannabigerol_on_experimental_inflammatory_bowel_disease#:~:text=,\" rel=\"noopener\" alt=\"https:\/\/www.researchgate.net\/publication\/235647806_Beneficial_effect_of_the_non-psychotropic_plant_cannabinoid_cannabigerol_on_experimental_inflammatory_bowel_disease#:~:text=,\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003eresearchgate.net\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/www.researchgate.net\/publication\/235647806_Beneficial_effect_of_the_non-psychotropic_plant_cannabinoid_cannabigerol_on_experimental_inflammatory_bowel_disease#:~:text=antagonist%29\" rel=\"noopener\" alt=\"https:\/\/www.researchgate.net\/publication\/235647806_Beneficial_effect_of_the_non-psychotropic_plant_cannabinoid_cannabigerol_on_experimental_inflammatory_bowel_disease#:~:text=antagonist%29\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003eresearchgate.net\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e)\u003c\/span\u003e\u003c\/span\u003e. Another study in a respiratory inflammation model found that when \u003cstrong data-start=\"5293\" data-end=\"5338\"\u003eproperly formulated for better absorption\u003c\/strong\u003e, both CBG and CBD sharply reduced inflammatory cell infiltration in lung tissue (cutting neutrophil counts by ~50% vs. placebo) (\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34082108\/#:~:text=in%20neutrophils%20found%20in%20bronchoalveolar,CBD%3ACBG%20%3D%201%3A1\" rel=\"noopener\" alt=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34082108\/#:~:text=in%20neutrophils%20found%20in%20bronchoalveolar,CBD%3ACBG%20%3D%201%3A1\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003epubmed.ncbi.nlm.nih.gov, \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34082108\/#:~:text=Conclusion%3A%20%20In%20conclusion%2C%20this,diseases%20characterised%20by%20airway%20inflammation\" rel=\"noopener\" alt=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34082108\/#:~:text=Conclusion%3A%20%20In%20conclusion%2C%20this,diseases%20characterised%20by%20airway%20inflammation\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003epubmed.ncbi.nlm.nih.gov\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e)\u003c\/span\u003e\u003c\/span\u003e. This shows their potential to ease inflammation in vivo. Excitingly, using CBD and CBG \u003cstrong data-start=\"5633\" data-end=\"5645\"\u003etogether\u003c\/strong\u003e may amplify pain relief: in one recent study of neuropathic pain in mice, a 1:1 combination of CBD+CBG produced a \u003cstrong data-start=\"5760\" data-end=\"5805\"\u003esynergistic reduction in pain sensitivity\u003c\/strong\u003e greater than either cannabinoid alone (\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38927352\/#:~:text=Figure%201\" rel=\"noopener\" alt=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38927352\/#:~:text=Figure%201\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003epubmed.ncbi.nlm.nih.gov\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e)\u003c\/span\u003e\u003c\/span\u003e. The two cannabinoids likely complement each other’s analgesic mechanisms, suggesting a broader relief spectrum – from dulling neuropathic pain signals to calming inflammatory pain – when used in tandem.\u003c\/p\u003e\n\u003cp data-start=\"6088\" data-end=\"7448\"\u003e\u003cstrong data-start=\"6088\" data-end=\"6128\"\u003ePhysiological Balance (Homeostasis):\u003c\/strong\u003e One of the hallmark benefits of cannabinoids is their ability to help maintain \u003cstrong data-start=\"6208\" data-end=\"6223\"\u003ehomeostasis\u003c\/strong\u003e, or equilibrium in the body’s systems. CBD and CBG act as modulators, restoring balance when systems are over- or under-active. CBG’s partial agonist activity at ECS receptors, along with its regulation of endocannabinoid tone, enables it to “fine-tune” various processes (\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/www.researchgate.net\/publication\/235647806_Beneficial_effect_of_the_non-psychotropic_plant_cannabinoid_cannabigerol_on_experimental_inflammatory_bowel_disease#:~:text=Show%20abstract\" rel=\"noopener\" alt=\"https:\/\/www.researchgate.net\/publication\/235647806_Beneficial_effect_of_the_non-psychotropic_plant_cannabinoid_cannabigerol_on_experimental_inflammatory_bowel_disease#:~:text=Show%20abstract\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003eresearchgate.net\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e)\u003c\/span\u003e\u003c\/span\u003e. CBD likewise has adaptogenic-like effects, influencing not only the ECS but also serotonin, adenosine, and other signaling systems to promote stability. Through these broad interactions, CBD and CBG can temper excesses – for instance, reducing an overactive stress response or hyperinflammation – while supporting functions that are lagging (such as mood or appetite). Many of the beneficial effects of cannabinoids in mood, immunity, metabolism, and neuroprotection stem from this \u003cstrong data-start=\"7018\" data-end=\"7039\"\u003ebalancing ability\u003c\/strong\u003e. By working on a cellular level to adjust neurotransmitter release, hormone levels, and immune mediator production, CBD and CBG help the body “reset” toward a healthy baseline. Users often report improved overall \u003cstrong data-start=\"7253\" data-end=\"7282\"\u003ewell-being and resilience\u003c\/strong\u003e with regular cannabinoid use, which aligns with these homeostatic properties (though more clinical research is needed to fully understand these adaptogenic effects).\u003c\/p\u003e\n\u003cp data-start=\"7450\" data-end=\"9471\"\u003e\u003cstrong data-start=\"7450\" data-end=\"7495\"\u003eAntioxidant and Immunomodulatory Effects:\u003c\/strong\u003e Both CBG and CBD exhibit significant \u003cstrong data-start=\"7533\" data-end=\"7557\"\u003eantioxidant capacity\u003c\/strong\u003e and the ability to modulate immune responses. Laboratory studies have shown that they can directly protect cells from oxidative stress. Notably, in one cell-culture experiment, CBG and CBD each \u003cstrong data-start=\"7752\" data-end=\"7803\"\u003ereduced levels of reactive oxygen species (ROS)\u003c\/strong\u003e in stressed human cells \u003cstrong data-start=\"7828\" data-end=\"7863\"\u003emore effectively than vitamin C\u003c\/strong\u003e, a classic antioxidant (\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35056807\/#:~:text=fibroblasts%20,weeks%20after%20sodium%20lauryl%20sulfate\" rel=\"noopener\" alt=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35056807\/#:~:text=fibroblasts%20,weeks%20after%20sodium%20lauryl%20sulfate\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003epubmed.ncbi.nlm.nih.gov\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e)\u003c\/span\u003e\u003c\/span\u003e. This suggests they can help neutralize harmful free radicals and oxidative byproducts that contribute to aging and tissue damage. In the same research, CBG also markedly \u003cstrong data-start=\"8097\" data-end=\"8137\"\u003einhibited pro-inflammatory cytokines\u003c\/strong\u003e (such as IL-1β, IL-6, IL-8, and TNF-α) released by cells under various inflammatory triggers (\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35056807\/#:~:text=fibroblasts%20,weeks%20after%20sodium%20lauryl%20sulfate\" rel=\"noopener\" alt=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35056807\/#:~:text=fibroblasts%20,weeks%20after%20sodium%20lauryl%20sulfate\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003epubmed.ncbi.nlm.nih.gov\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e)\u003c\/span\u003e\u003c\/span\u003e. Interestingly, CBG outperformed CBD in suppressing certain inflammatory signals in that model, indicating it’s a potent immunomodulator. Other studies reinforce these findings – for example, CBG has been shown to \u003cstrong data-start=\"8484\" data-end=\"8537\"\u003eincrease anti-inflammatory interleukin-10 (IL-10)\u003c\/strong\u003e while normalizing levels of pro-inflammatory molecules like IL-1β and IFN-γ in an inflamed colon tissue model (\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/www.researchgate.net\/publication\/235647806_Beneficial_effect_of_the_non-psychotropic_plant_cannabinoid_cannabigerol_on_experimental_inflammatory_bowel_disease#:~:text=,\" rel=\"noopener\" alt=\"https:\/\/www.researchgate.net\/publication\/235647806_Beneficial_effect_of_the_non-psychotropic_plant_cannabinoid_cannabigerol_on_experimental_inflammatory_bowel_disease#:~:text=,\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003eresearchgate.net\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/www.researchgate.net\/publication\/235647806_Beneficial_effect_of_the_non-psychotropic_plant_cannabinoid_cannabigerol_on_experimental_inflammatory_bowel_disease#:~:text=,90%5D.\" rel=\"noopener\" alt=\"https:\/\/www.researchgate.net\/publication\/235647806_Beneficial_effect_of_the_non-psychotropic_plant_cannabinoid_cannabigerol_on_experimental_inflammatory_bowel_disease#:~:text=,90%5D.\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003eresearchgate.net\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e)\u003c\/span\u003e\u003c\/span\u003e. Meanwhile, CBD is well documented to alter cytokine production and support a balanced immune response (it’s being explored for autoimmune and neuroinflammatory conditions for this reason). Both cannabinoids have also demonstrated \u003cstrong data-start=\"8957\" data-end=\"8976\"\u003eneuroprotective\u003c\/strong\u003e effects, thought to be due to a combination of reducing oxidative stress and calming excessive inflammation in the brain. The takeaway is that CBD and CBG can act as cell protectants – they help shield tissues from oxidative damage and prevent overactive immune responses that can harm the body. This antioxidant and immunomodulatory activity further supports their use in wellness formulations aimed at reducing inflammation, supporting immunity, and promoting longevity at the cellular level.\u003c\/p\u003e\n\u003cp data-start=\"9473\" data-end=\"9515\"\u003e🦷 \u003cstrong data-start=\"9476\" data-end=\"9515\"\u003eCBD + CBG in Oral Care Applications\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-start=\"9517\" data-end=\"9774\"\u003eThe combination of CBD and CBG is particularly promising in \u003cstrong data-start=\"9577\" data-end=\"9590\"\u003eoral care\u003c\/strong\u003e products, thanks to their antimicrobial, anti-inflammatory, and soothing properties. Recent studies have started to evaluate cannabinoids for use in the mouth – with exciting results:\u003c\/p\u003e\n\u003cp data-start=\"9776\" data-end=\"11287\"\u003e\u003cstrong data-start=\"9776\" data-end=\"9801\"\u003eAntibacterial Action:\u003c\/strong\u003e Both CBG and CBD display significant \u003cstrong data-start=\"9839\" data-end=\"9865\"\u003eantimicrobial activity\u003c\/strong\u003e against common oral pathogens. CBG in particular has been shown to \u003cstrong data-start=\"9933\" data-end=\"9978\"\u003ehalt the growth of \u003cem data-start=\"9954\" data-end=\"9976\"\u003eStreptococcus mutans \u003c\/em\u003e\u003c\/strong\u003e(\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33967995\/#:~:text=phytocannabinoid%20Cannabigerol%20%28CBG%29,treated%20bacteria\" rel=\"noopener\" alt=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33967995\/#:~:text=phytocannabinoid%20Cannabigerol%20%28CBG%29,treated%20bacteria\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003epubmed.ncbi.nlm.nih.gov\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e)\u003c\/span\u003e\u003c\/span\u003e, the primary bacteria responsible for dental plaque and cavities. Treated \u003cem data-start=\"10092\" data-end=\"10103\"\u003eS. mutans\u003c\/em\u003e cells exhibit disrupted, swollen membranes and increased permeability, indicating CBG literally compromises the bacterial cell membrane (\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33967995\/#:~:text=phytocannabinoid%20Cannabigerol%20%28CBG%29,and%20reduced%20calcein%20AM%20staining\" rel=\"noopener\" alt=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33967995\/#:~:text=phytocannabinoid%20Cannabigerol%20%28CBG%29,and%20reduced%20calcein%20AM%20staining\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003epubmed.ncbi.nlm.nih.gov\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e)\u003c\/span\u003e\u003c\/span\u003e. CBD similarly has broad antibacterial effects on oral microbes. In fact, a head-to-head laboratory study found that cannabinoid-infused oral rinses were able to \u003cstrong data-start=\"10441\" data-end=\"10547\"\u003einhibit dental plaque bacteria as effectively as or better than standard chlorhexidine (CHX) mouthwash \u003c\/strong\u003e(\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33526124\/#:~:text=Results%3A%20%20On%20average%2C%20the,8%20mm\" rel=\"noopener\" alt=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33526124\/#:~:text=Results%3A%20%20On%20average%2C%20the,8%20mm\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003epubmed.ncbi.nlm.nih.gov, \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33526124\/#:~:text=inhibition%20zone%20at%20all%20in,with%20natural%20key%20ingredients%20including\" rel=\"noopener\" alt=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33526124\/#:~:text=inhibition%20zone%20at%20all%20in,with%20natural%20key%20ingredients%20including\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003epubmed.ncbi.nlm.nih.gov\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e)\u003c\/span\u003e\u003c\/span\u003e. Both a CBD-based and a CBG-based mouthwash showed \u003cstrong data-start=\"10677\" data-end=\"10727\"\u003ezones of bacterial growth inhibition ~17–18 mm\u003c\/strong\u003e, comparable to (even slightly larger than) the ~16.8 mm zones with prescription-strength CHX (\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33526124\/#:~:text=inhibition%20zone%20at%20all%20in,with%20natural%20key%20ingredients%20including\" rel=\"noopener\" alt=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33526124\/#:~:text=inhibition%20zone%20at%20all%20in,with%20natural%20key%20ingredients%20including\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003epubmed.ncbi.nlm.nih.gov\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e)\u003c\/span\u003e\u003c\/span\u003e. Crucially, the cannabinoid formulas were effective against \u003cem data-start=\"10920\" data-end=\"10925\"\u003eall\u003c\/em\u003e the plaque samples tested (\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33526124\/#:~:text=Results%3A%20%20On%20average%2C%20the,8%20mm\" rel=\"noopener\" alt=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33526124\/#:~:text=Results%3A%20%20On%20average%2C%20the,8%20mm\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003epubmed.ncbi.nlm.nih.gov\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e)\u003c\/span\u003e\u003c\/span\u003e, suggesting a broad spectrum of action. This antimicrobial potency means that a \u003cstrong data-start=\"11071\" data-end=\"11121\"\u003eCBD+CBG oral product could help control plaque\u003c\/strong\u003e, reduce oral bacteria load, and combat issues like tooth decay, gum disease, and even bad breath – all without the use of traditional antibiotics or harsh chemicals.\u003c\/p\u003e\n\u003cp data-start=\"11289\" data-end=\"12786\"\u003e\u003cstrong data-start=\"11289\" data-end=\"11339\"\u003eComparable to Chlorhexidine, Without Staining:\u003c\/strong\u003e Chlorhexidine digluconate is a gold-standard antiseptic in mouthwash, but long-term use is notorious for causing \u003cstrong data-start=\"11453\" data-end=\"11491\"\u003ebrown staining of teeth and tongue\u003c\/strong\u003e, as well as altering taste. One big advantage of cannabinoids like CBD and CBG is that they do \u003cstrong data-start=\"11587\" data-end=\"11620\"\u003enot cause tooth discoloration\u003c\/strong\u003e or taste perturbation. The study mentioned above pointed out that CHX’s tendency to cause staining is a significant drawback, and that \u003cstrong data-start=\"11756\" data-end=\"11813\"\u003ecannabinoid mouthwashes provide a natural alternative\u003c\/strong\u003e without this issue (\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/www.dental-tribune.com\/news\/cannabinoids-fight-plaque-as-effectively-as-chlorhexidine-in-mouthwash-study\/#:~:text=Synthetic%20cannabinoids%20have%20been%20shown,therefore%20be%20an%20appealing%20alternative\" rel=\"noopener\" alt=\"https:\/\/www.dental-tribune.com\/news\/cannabinoids-fight-plaque-as-effectively-as-chlorhexidine-in-mouthwash-study\/#:~:text=Synthetic%20cannabinoids%20have%20been%20shown,therefore%20be%20an%20appealing%20alternative\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003edental-tribune.com\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e)\u003c\/span\u003e\u003c\/span\u003e. Users can get antiseptic benefits similar to a medicated rinse but \u003cem data-start=\"11940\" data-end=\"11949\"\u003ewithout\u003c\/em\u003e the cosmetic downsides – cannabinoid formulations are typically colorless and non-irritating. Additionally, many conventional mouthwashes rely on alcohol for antimicrobial action, which can dry out and irritate the mouth. CBD\/CBG oral products are \u003cstrong data-start=\"12198\" data-end=\"12214\"\u003ealcohol-free\u003c\/strong\u003e (often oil-based or water-based with gentle emulsifiers), avoiding the burning sensation and dry mouth effect. This means a CBD+CBG mouthwash or oral oil can be used daily for plaque control and gum health, with a pleasant user experience (no harsh burn, no lingering medicinal aftertaste, and no yellowing of teeth). In short, \u003cstrong data-start=\"12543\" data-end=\"12599\"\u003eCBD and CBG offer a gentler approach to oral hygiene\u003c\/strong\u003e – comparable efficacy to established agents like chlorhexidine (\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33526124\/#:~:text=inhibition%20zone%20at%20all%20in,with%20natural%20key%20ingredients%20including\" rel=\"noopener\" alt=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33526124\/#:~:text=inhibition%20zone%20at%20all%20in,with%20natural%20key%20ingredients%20including\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003epubmed.ncbi.nlm.nih.gov\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e)\u003c\/span\u003e\u003c\/span\u003e, but without the side effects that make people reluctant to use mouthwash long-term.\u003c\/p\u003e\n\u003cp data-start=\"12788\" data-end=\"14521\"\u003e\u003cstrong data-start=\"12788\" data-end=\"12834\"\u003eSoothing \u0026amp; Well Tolerated by Oral Tissues:\u003c\/strong\u003e Another benefit of incorporating CBD and CBG in oral care is their \u003cstrong data-start=\"12902\" data-end=\"12928\"\u003eexcellent tolerability\u003c\/strong\u003e. These cannabinoids are \u003cstrong data-start=\"12953\" data-end=\"12990\"\u003enon-irritating to the oral mucosa\u003c\/strong\u003e; in fact, they may help soothe inflammation in gums and soft tissues. Studies on topical use have shown cannabinoids to be safe and even healing for skin and mucous membranes. For example, a clinical study of a CBG topical serum (0.1% CBG) found it actually \u003cstrong data-start=\"13249\" data-end=\"13296\"\u003ereduced redness and improved skin hydration\u003c\/strong\u003e in irritated skin, compared to placebo (\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35056807\/#:~:text=oxidative%20stress,of%20in%20vitro%20and%20clinical\" rel=\"noopener\" alt=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35056807\/#:~:text=oxidative%20stress,of%20in%20vitro%20and%20clinical\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003epubmed.ncbi.nlm.nih.gov, \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35056807\/#:~:text=CBD.%20A%2020,be%20more%20effective%20than%20CBD\" rel=\"noopener\" alt=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35056807\/#:~:text=CBD.%20A%2020,be%20more%20effective%20than%20CBD\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003epubmed.ncbi.nlm.nih.gov\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e)\u003c\/span\u003e\u003c\/span\u003e – indicating CBG helped calm inflammation and restore the skin barrier. By extension, when applied in the mouth, CBG and CBD can similarly ease minor gum inflammation or irritation (such as from gingivitis or after dental procedures). Users of cannabinoid oral oils often report a soothing effect on sore gums or sensitivity. Importantly, no significant adverse effects like oral burning, mouth ulcers, or tissue damage have been reported with cannabinoid oral care products. In a trial of cannabinoid mouthwashes, participants experienced no negative reactions; the authors noted the products were a \u003cstrong data-start=\"14015\" data-end=\"14047\"\u003e“safer, natural alternative”\u003c\/strong\u003e for oral health maintenance (\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/www.dental-tribune.com\/news\/cannabinoids-fight-plaque-as-effectively-as-chlorhexidine-in-mouthwash-study\/#:~:text=ANTWERP%2C%20Belgium%3A%20An%20industry,containing%20mouthwash%20products\" rel=\"noopener\" alt=\"https:\/\/www.dental-tribune.com\/news\/cannabinoids-fight-plaque-as-effectively-as-chlorhexidine-in-mouthwash-study\/#:~:text=ANTWERP%2C%20Belgium%3A%20An%20industry,containing%20mouthwash%20products\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003edental-tribune.com, \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/www.dental-tribune.com\/news\/cannabinoids-fight-plaque-as-effectively-as-chlorhexidine-in-mouthwash-study\/#:~:text=On%20average%2C%20the%20products%20infused,any%20of%20the%20tested%20samples\" rel=\"noopener\" alt=\"https:\/\/www.dental-tribune.com\/news\/cannabinoids-fight-plaque-as-effectively-as-chlorhexidine-in-mouthwash-study\/#:~:text=On%20average%2C%20the%20products%20infused,any%20of%20the%20tested%20samples\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003edental-tribune.com\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e)\u003c\/span\u003e\u003c\/span\u003e. CBD and CBG lack the abrasiveness or astringency of some traditional oral ingredients, making them gentle enough for those with sensitive mouths. Overall, a CBD+CBG oral formula is expected to be \u003cstrong data-start=\"14351\" data-end=\"14374\"\u003every well tolerated\u003c\/strong\u003e – providing benefits to the gums and oral tissue (through anti-inflammatory and antimicrobial action) while being soothing rather than irritating.\u003c\/p\u003e\n\u003cp data-start=\"14523\" data-end=\"16137\"\u003e\u003cstrong data-start=\"14523\" data-end=\"14560\"\u003eFormulation Stability \u0026amp; Delivery:\u003c\/strong\u003e Because CBD and CBG are lipophilic (fat-loving) molecules, formulating them correctly is key for effective oral use. They are most stable and bioavailable when delivered in a lipid or emulsified carrier. This product has been formulated using nourishing carrier oils (like MCT coconut oil) to \u003cstrong data-start=\"14854\" data-end=\"14899\"\u003esolubilize and stabilize the cannabinoids\u003c\/strong\u003e, protecting them from degradation and ensuring they are readily absorbed into the oral tissues. A proper formulation also allows the CBD and CBG to \u003cstrong data-start=\"15048\" data-end=\"15082\"\u003ecoat the teeth and gums evenly\u003c\/strong\u003e, maximizing contact time with microbial plaque and inflamed areas. Research shows that using appropriate carriers or surfactants can dramatically improve cannabinoid delivery and efficacy (\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34082108\/#:~:text=in%20neutrophils%20found%20in%20bronchoalveolar,CBD%3ACBG%20%3D%201%3A1\" rel=\"noopener\" alt=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34082108\/#:~:text=in%20neutrophils%20found%20in%20bronchoalveolar,CBD%3ACBG%20%3D%201%3A1\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003epubmed.ncbi.nlm.nih.gov, \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34082108\/#:~:text=any%20significant%20effects%20on%20the,induced%20neutrophilia.%20Surfactants%2C%20such%20as\" rel=\"noopener\" alt=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34082108\/#:~:text=any%20significant%20effects%20on%20the,induced%20neutrophilia.%20Surfactants%2C%20such%20as\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003epubmed.ncbi.nlm.nih.gov\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e)\u003c\/span\u003e\u003c\/span\u003e. (For instance, one study noted that an MCT-oil formulation of CBD\/CBG had limited effect in a model, whereas a surfactant-enhanced formulation achieved significant anti-inflammatory results (\u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34082108\/#:~:text=in%20neutrophils%20found%20in%20bronchoalveolar,CBD%3ACBG%20%3D%201%3A1\" rel=\"noopener\" alt=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34082108\/#:~:text=in%20neutrophils%20found%20in%20bronchoalveolar,CBD%3ACBG%20%3D%201%3A1\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\" target=\"_blank\"\u003e\u003cspan class=\"relative start-0 bottom-0 flex h-full w-full items-center\"\u003e\u003cspan class=\"flex h-4 w-full items-center justify-between overflow-hidden\"\u003e\u003cspan class=\"max-w-full grow truncate overflow-hidden text-center\"\u003epubmed.ncbi.nlm.nih.gov\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e)\u003c\/span\u003e\u003c\/span\u003e – underscoring the importance of formulation technique.) In our case, the combination of CBD and CBG is incorporated into a smooth oil-based solution that keeps the actives potent and bioavailable. This not only preserves the cannabinoids’ benefits over the product’s shelf life but also facilitates their \u003cstrong data-start=\"15885\" data-end=\"15937\"\u003epenetration into plaque biofilm and gum crevices\u003c\/strong\u003e when used. The end result is a stable, effective oral care product: CBD and CBG remain active from the first drop to the last, delivering full antimicrobial and soothing action every time you use it.\u003c\/p\u003e\n\u003cblockquote data-start=\"16139\" data-end=\"16403\"\u003e\n\u003cp data-start=\"16141\" data-end=\"16403\"\u003e\u003cstrong data-start=\"16141\" data-end=\"16150\"\u003eNote:\u003c\/strong\u003e This is registered in the European CPNP database with Notification Number: CPNP 4680818.\u003c\/p\u003e\n\u003c\/blockquote\u003e\n\u003cp data-start=\"16405\" data-end=\"16725\"\u003eThe information provided above is based on published scientific literature about cannabidiol (CBD) and cannabigerol (CBG) as compounds. It is presented for educational purposes and should not be interpreted as a health claim for the product. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/p\u003e\n\u003cp data-start=\"16727\" data-end=\"16744\"\u003e📚 \u003cstrong data-start=\"16730\" data-end=\"16744\"\u003eReferences\u003c\/strong\u003e\u003c\/p\u003e\n\u003col data-start=\"16746\" data-end=\"17958\" data-is-last-node=\"\" data-is-only-node=\"\"\u003e\n\u003cli data-start=\"16746\" data-end=\"16896\"\u003e\n\u003cp data-start=\"16749\" data-end=\"16896\"\u003eCalapai, F., et al. (2022). \u003cem data-start=\"16777\" data-end=\"16832\"\u003eEvidence-Based Complementary and Alternative Medicine\u003c\/em\u003e, 2022, Article ID 3336516. \u003ca rel=\"noopener\" title=\"cbg\" href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2022\/3336516\" target=\"_blank\"\u003e\u003cspan href=\"https:\/\/doi.org\/10.1155\/2022\/3336516\" data-start=\"16860\" data-end=\"16896\" rel=\"noopener noreferrer\"\u003ehttps:\/\/doi.org\/10.1155\/2022\/3336516\u003c\/span\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"16898\" data-end=\"17042\"\u003e\n\u003cp data-start=\"16901\" data-end=\"17042\"\u003eGrinspoon, P. (2021). Harvard Health Publishing – \u003cem data-start=\"16951\" data-end=\"17006\"\u003eThe endocannabinoid system: Essential and mysterious.\u003c\/em\u003e (Blog article) Harvard Health Blog.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"17044\" data-end=\"17154\"\u003e\n\u003cp data-start=\"17047\" data-end=\"17154\"\u003eCuttler, C., et al. (2024). \u003cem data-start=\"17075\" data-end=\"17095\"\u003eScientific Reports\u003c\/em\u003e, \u003cstrong data-start=\"17097\" data-end=\"17103\"\u003e14\u003c\/strong\u003e, 16163. \u003ca rel=\"noopener\" title=\"cbg\" href=\"https:\/\/www.nature.com\/articles\/s41598-024-66879-0\" target=\"_blank\"\u003e\u003cspan href=\"https:\/\/doi.org\/10.1038\/s41598-024-66879-0\" data-start=\"17112\" data-end=\"17154\" rel=\"noopener noreferrer\"\u003ehttps:\/\/doi.org\/10.1038\/s41598-024-66879-0\u003c\/span\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"17156\" data-end=\"17281\"\u003e\n\u003cp data-start=\"17159\" data-end=\"17281\"\u003eRusso, E. B., et al. (2022). \u003cem data-start=\"17188\" data-end=\"17223\"\u003eCannabis and Cannabinoid Research\u003c\/em\u003e, \u003cstrong data-start=\"17225\" data-end=\"17230\"\u003e7\u003c\/strong\u003e(4), 706–716. \u003ca rel=\"noopener\" title=\"cbg\" href=\"https:\/\/www.liebertpub.com\/doi\/10.1089\/can.2021.0058\" target=\"_blank\"\u003e\u003cspan href=\"https:\/\/doi.org\/10.1089\/can.2021.0058\" data-start=\"17244\" data-end=\"17281\" rel=\"noopener noreferrer\"\u003ehttps:\/\/doi.org\/10.1089\/can.2021.0058\u003c\/span\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"17283\" data-end=\"17406\"\u003e\n\u003cp data-start=\"17286\" data-end=\"17406\"\u003eBorrelli, F., et al. (2013). \u003cem data-start=\"17315\" data-end=\"17341\"\u003eBiochemical Pharmacology\u003c\/em\u003e, \u003cstrong data-start=\"17343\" data-end=\"17349\"\u003e85\u003c\/strong\u003e(9), 1306–1316. \u003ca rel=\"noopener\" title=\"cbg\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0006295213000543?via%3Dihub\" target=\"_blank\"\u003e\u003cspan href=\"https:\/\/doi.org\/10.1016\/j.bcp.2013.01.017\" data-start=\"17365\" data-end=\"17406\" rel=\"noopener noreferrer\"\u003ehttps:\/\/doi.org\/10.1016\/j.bcp.2013.01.017\u003c\/span\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"17408\" data-end=\"17507\"\u003e\n\u003cp data-start=\"17411\" data-end=\"17507\"\u003ePerez, E., et al. (2022). \u003cem data-start=\"17437\" data-end=\"17448\"\u003eMolecules\u003c\/em\u003e, \u003cstrong data-start=\"17450\" data-end=\"17456\"\u003e27\u003c\/strong\u003e(2), 491. \u003ca rel=\"noopener\" title=\"cbg\" href=\"https:\/\/www.mdpi.com\/1420-3049\/27\/2\/491\" target=\"_blank\"\u003e\u003cspan href=\"https:\/\/doi.org\/10.3390\/molecules27020491\" data-start=\"17466\" data-end=\"17507\" rel=\"noopener noreferrer\"\u003ehttps:\/\/doi.org\/10.3390\/molecules27020491\u003c\/span\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"17509\" data-end=\"17624\"\u003e\n\u003cp data-start=\"17512\" data-end=\"17624\"\u003eAqawi, M., et al. (2021). \u003cem data-start=\"17538\" data-end=\"17565\"\u003eFrontiers in Microbiology\u003c\/em\u003e, \u003cstrong data-start=\"17567\" data-end=\"17573\"\u003e12\u003c\/strong\u003e, 656471. \u003ca rel=\"noopener\" title=\"cbg\" href=\"https:\/\/www.frontiersin.org\/journals\/microbiology\/articles\/10.3389\/fmicb.2021.656471\/full\" target=\"_blank\"\u003e\u003cspan href=\"https:\/\/doi.org\/10.3389\/fmicb.2021.656471\" data-start=\"17583\" data-end=\"17624\" rel=\"noopener noreferrer\"\u003ehttps:\/\/doi.org\/10.3389\/fmicb.2021.656471\u003c\/span\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"17626\" data-end=\"17752\"\u003e\n\u003cp data-start=\"17629\" data-end=\"17752\"\u003eVasudevan, K., \u0026amp; Stahl, V. (2020). \u003cem data-start=\"17664\" data-end=\"17694\"\u003eJournal of Cannabis Research\u003c\/em\u003e, \u003cstrong data-start=\"17696\" data-end=\"17701\"\u003e2\u003c\/strong\u003e(1), 20. \u003ca rel=\"noopener\" title=\"cbd\" href=\"https:\/\/jcannabisresearch.biomedcentral.com\/articles\/10.1186\/s42238-020-00027-z\" target=\"_blank\"\u003e\u003cspan href=\"https:\/\/doi.org\/10.1186\/s42238-020-00027-z\" data-start=\"17710\" data-end=\"17752\" rel=\"noopener noreferrer\"\u003ehttps:\/\/doi.org\/10.1186\/s42238-020-00027-z\u003c\/span\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"17754\" data-end=\"17851\"\u003e\n\u003cp data-start=\"17757\" data-end=\"17851\"\u003eRegulation (EU) No 1307\/2013 and Directive 2002\/46\/EC – EU compliance on hemp and novel foods.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"17853\" data-end=\"17958\" data-is-last-node=\"\"\u003e\n\u003cp data-start=\"17857\" data-end=\"17958\" data-is-last-node=\"\"\u003eCPNP Notification Number: 4680818 (Product registration in EU Cosmetic Products Notification Portal).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"CRETAN GAIA PRODUCTS","offers":[{"title":"Default Title","offer_id":53231331082568,"sku":"CG2955","price":28.53,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0968\/7603\/6424\/files\/MAGICPAIR.jpg?v=1780577080"},{"product_id":"natura-inside-broad-spectrum-cannabis-oil-10-cbd-with-piperine-phytorelax-series-10ml","title":"Natura Inside Broad Spectrum Cannabis Oil – 10% CBD with Piperine, Phytorelax Series, 10ml","description":"\u003ch3\u003e\u003cstrong\u003eCBD Oil 10% (10ml)\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eThis high-concentration oil contains \u003cstrong\u003e10% CBD (1000 mg per 10 ml)\u003c\/strong\u003e, derived from \u003cem\u003eCannabis sativa L.\u003c\/em\u003e, and is formulated with a \u003cstrong\u003ebroad spectrum of natural cannabinoids\u003c\/strong\u003e, terpenes, and other plant compounds. It offers a \u003cstrong\u003eclean botanical profile\u003c\/strong\u003e, enriched with \u003cstrong\u003epiperine\u003c\/strong\u003e for enhanced composition.\u003c\/p\u003e\n\u003chr\u003e\n\u003cp\u003e🌿 \u003cstrong\u003eKey Features\u003c\/strong\u003e\u003cbr\u003e• 10% CBD – 1000 mg per 10 ml\u003cbr\u003e• Broad-spectrum extract from \u003cem\u003eCannabis sativa L.\u003c\/em\u003e\u003cbr\u003e• Contains piperine (black pepper extract)\u003cbr\u003e• Natural carrier oils: MCT (C8\/C10 triglycerides) derived from coconut oil, Greek olive oil, and cold-pressed sunflower oil\u003cbr\u003e• Neutral, earthy taste from plant terpenes\u003cbr\u003e• No artificial ingredients, preservatives, or solvents\u003c\/p\u003e\n\u003chr\u003e\n\u003cp\u003e🧪 \u003cstrong data-start=\"99\" data-end=\"113\"\u003eHow to Use\u003c\/strong\u003e\u003cbr data-start=\"113\" data-end=\"116\"\u003e• Shake well before use\u003cbr data-start=\"139\" data-end=\"142\"\u003e• Apply a small amount 2–3 times daily, preferably every day\u003cbr data-start=\"280\" data-end=\"283\"\u003e• Store in a cool, dark place at room temperature (15–25 °C)\u003c\/p\u003e\n\u003cp data-start=\"98\" data-end=\"243\"\u003e\u003cem data-start=\"121\" data-end=\"241\"\u003eWant to learn more about cannabidiol and its properties in oral care and wellness products? Check out this short blog.\u003c\/em\u003e\u003c\/p\u003e\n\u003chr\u003e\n\u003ch3\u003e🧬 \u003cstrong\u003eCannabidiol (CBD) and Scientifically Documented Properties\u003c\/strong\u003e\n\u003c\/h3\u003e\n\u003cp\u003eCannabidiol (CBD) is a natural phytocannabinoid derived from the \u003cem\u003eCannabis sativa\u003c\/em\u003e plant. Unlike tetrahydrocannabinol (THC), CBD is \u003cstrong\u003enon-psychoactive\u003c\/strong\u003e, making it safe for daily use¹. It interacts with the \u003cstrong\u003eendocannabinoid system (ECS)\u003c\/strong\u003e, which regulates key physiological functions such as anxiety, pain, sleep, and immune balance².\u003c\/p\u003e\n\u003chr\u003e\n\u003cp\u003e📌 \u003cstrong\u003eKey Properties Identified in Scientific Literature:\u003c\/strong\u003e\u003cbr\u003e• \u003cstrong\u003eAnxiety and stress relief\u003c\/strong\u003e: CBD appears to interact with serotonin receptors, contributing to anxiolytic effects³. It has been studied in cases of social anxiety, generalized anxiety disorder, and PTSD.\u003cbr\u003e• \u003cstrong\u003eSleep support\u003c\/strong\u003e: Research shows that CBD may improve sleep quality and duration, particularly when sleep disturbances are related to anxiety⁴.\u003cbr\u003e• \u003cstrong\u003eAnti-inflammatory and analgesic properties\u003c\/strong\u003e: CBD influences CB1, CB2, and TRPV1 receptors, supporting relief from chronic or neuropathic pain and reducing inflammation⁵.\u003cbr\u003e• \u003cstrong\u003ePhysiological balance (homeostasis)\u003c\/strong\u003e: By modulating the ECS, CBD may help support general wellbeing and internal balance⁶.\u003cbr\u003e• \u003cstrong\u003eAntioxidant and immunomodulatory effects\u003c\/strong\u003e: Experimental data suggest CBD may reduce pro-inflammatory cytokines and support immune response⁷.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch3\u003e🦷 \u003cstrong\u003eCBD in Oral Care Applications\u003c\/strong\u003e\n\u003c\/h3\u003e\n\u003cp\u003eRecent \u003cstrong\u003ein vitro\u003c\/strong\u003e studies have evaluated CBD for topical use in the oral cavity due to its \u003cstrong\u003eantimicrobial, anti-inflammatory, and soothing properties⁸\u003c\/strong\u003e:\u003c\/p\u003e\n\u003cp\u003e• Shows antimicrobial activity against common oral pathogens such as \u003cem\u003eStreptococcus mutans\u003c\/em\u003e and \u003cem\u003ePorphyromonas gingivalis⁸\u003c\/em\u003e\u003cbr\u003e• Demonstrates effects comparable or superior to chlorhexidine, without side effects like staining⁹\u003cbr\u003e• Well tolerated by oral tissues — no irritation, burning, or discoloration⁸\u003cbr\u003e• Effectively stabilized in carrier oils such as MCT and olive oil, which enhance delivery in oral formulations⁸\u003c\/p\u003e\n\u003chr\u003e\n\u003cp\u003e\u003cstrong\u003eNote:\u003c\/strong\u003e This product is registered in the European CPNP database with \u003cstrong\u003eNotification Number: CPNP 4470959\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cp\u003eThe information presented is based on published scientific literature regarding \u003cstrong\u003ecannabidiol (CBD)\u003c\/strong\u003e as a compound and \u003cstrong\u003edoes not constitute a health claim\u003c\/strong\u003e for the final product. This product is \u003cstrong\u003enot intended to diagnose, treat, cure, or prevent any disease\u003c\/strong\u003e.\u003c\/p\u003e\n\u003chr\u003e\n\u003cp\u003e📚 \u003cstrong\u003eReferences\u003c\/strong\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cp\u003eWorld Health Organization. (2018). \u003cem\u003eCannabidiol (CBD) Critical Review Report\u003c\/em\u003e.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eLowe, H. I. C., Toyang, N. J., \u0026amp; McLaughlin, W. (2021). \u003cem\u003eMedicines\u003c\/em\u003e, 8(6), 44. \u003ca href=\"https:\/\/doi.org\/10.3390\/molecules26237216\"\u003ehttps:\/\/doi.org\/10.3390\/medicines8060044\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eBlessing, E. M., et al. (2015). \u003cem\u003eNeurotherapeutics\u003c\/em\u003e, 12(4), 825–836. \u003ca href=\"https:\/\/doi.org\/10.1007\/s13311-015-0387-1\"\u003ehttps:\/\/doi.org\/10.1007\/s13311-015-0387-1\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eShannon, S., et al. (2019). \u003cem\u003eThe Permanente Journal\u003c\/em\u003e, 23. \u003ca href=\"https:\/\/doi.org\/10.7812\/TPP\/18-041\"\u003ehttps:\/\/doi.org\/10.7812\/TPP\/18-041\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eWhiting, P. F., et al. (2015). \u003cem\u003eJAMA\u003c\/em\u003e, 313(24), 2456–2473. \u003ca href=\"https:\/\/doi.org\/10.1001\/jama.2015.6358\"\u003ehttps:\/\/doi.org\/10.1001\/jama.2015.6358\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eNichols, J. M., \u0026amp; Kaplan, B. L. (2020). \u003cem\u003eCannabis and Cannabinoid Research\u003c\/em\u003e, 5(1), 12–31. \u003ca href=\"https:\/\/doi.org\/10.1089\/can.2018.0073\"\u003ehttps:\/\/doi.org\/10.1089\/can.2018.0073\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eKozela, E., et al. (2011). \u003cem\u003eJournal of Neuroimmune Pharmacology\u003c\/em\u003e, 6(3), 529–540. \u003ca href=\"https:\/\/doi.org\/10.1111\/j.1476-5381.2011.01379.x\" aria-label=\"Digital Object Identifier for Cannabidiol inhibits pathogenic T cells, decreases spinal microglial activation and ameliorates multiple sclerosis-like disease in C57BL\/6 mice link\" class=\"epub-doi\"\u003ehttps:\/\/doi.org\/10.1111\/j.1476-5381.2011.01379.x\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eStahl, V., \u0026amp; Vasudevan, K. (2020). \u003cem\u003eCureus\u003c\/em\u003e, 12(1), e6809. \u003ca href=\"https:\/\/doi.org\/10.7759\/cureus.6809\"\u003ehttps:\/\/doi.org\/10.7759\/cureus.6809\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eIffland, K., \u0026amp; Grotenhermen, F. (2017). \u003cem\u003eCannabis and Cannabinoid Research\u003c\/em\u003e, 2(1), 139–154. \u003ca href=\"https:\/\/doi.org\/10.1089\/can.2016.0034\"\u003ehttps:\/\/doi.org\/10.1089\/can.2016.0034\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eRegulation (EU) No 1307\/2013 and Directive 2002\/46\/EC – \u003cstrong\u003eEU compliance on hemp and novel foods\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"Natura Inside","offers":[{"title":"Default Title","offer_id":53231331410248,"sku":"LA2910broad","price":12.44,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0968\/7603\/6424\/files\/phytorelax10_NewForm.jpg?v=1780577089"}],"url":"https:\/\/sojsupplements.com\/collections\/frontpage.oembed","provider":"SOJ Supplements","version":"1.0","type":"link"}